Welcome to LookChem.com Sign In|Join Free

Cas Database

3168-90-9

3168-90-9

Identification

  • Product Name:Ethanone,1-(2-methyl-1-cyclopenten-1-yl)-

  • CAS Number: 3168-90-9

  • EINECS:

  • Molecular Weight:124.183

  • Molecular Formula: C8H12 O

  • HS Code:2914299000

  • Mol File:3168-90-9.mol

Synonyms:Ketone,methyl 2-methyl-1-cyclopenten-1-yl (6CI,7CI,8CI);1-Acetyl-2-methyl-1-cyclopentene; 1-Acetyl-2-methylcyclopentene

Post Buying Request Now
Entrust LookChem procurement to find high-quality suppliers faster

Safety information and MSDS view more

  • Signal Word:no data available

  • Hazard Statement:no data available

  • First-aid measures: General adviceConsult a physician. Show this safety data sheet to the doctor in attendance.If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

  • Fire-fighting measures: Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.

  • Accidental release measures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

  • Handling and storage: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

  • Exposure controls/personal protection:Occupational Exposure limit valuesBiological limit values Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Eye/face protection Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Respiratory protection Wear dust mask when handling large quantities. Thermal hazards

Supplier and reference price

  • Manufacture/Brand
  • Product Description
  • Packaging
  • Price
  • Delivery
  • Purchase
  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:1-ACETYL-2-METHYL-1-CYCLOPENTENE Aldrich
  • Packaging:100mg
  • Price:$ 139
  • Delivery:In stock
  • Buy Now

Relevant articles and documentsAll total 18 Articles be found

Theoretical Study of Intramolecular Aldol Condensation of 1,6-Diketones: Trimethylsilyl Substituent Effect

Bouillon, Jean-Philippe,Portella, Charles,Bouquant, James,Humbel, Stephane

, p. 5823 - 5830 (2000)

Diastereoselective intramolecular aldol condensations are investigated in an experimental and computational study of 1,6-diketones. Ab initio results show the importance of the acid medium and disapprove the possibility of a spontaneous cyclization, even for silylated compounds. The combination of both experimental and computational approaches brings valuable information on the mechanism and on the selectivity of the aldol reaction. It is found that the enolization of the diketone is a key step in acid-catalyzed mechanism. The cyclization step bears a very small activation energy. The dehydration of the aldols are discussed.

Formal total synthesis of (±)-trichodiene via Claisen rearrangement and Robinson annulation

Jung, Jae-Chul,Jung, Young-Jo,Park, Oee-Sook

, p. 293 - 297 (2008)

A facile formal total synthesis of (±)-trichodiene was achieved by employing Claisen rearrangement and Robinson annulation as synthetic key strategies.

(Trimethylsilyl)cyclopentene Annulation: A Regiocontrolled Approach to the Synthesis of Five-Membered Rings

Danheiser, Rick L.,Carini, David J.,Basak, Ajoy

, p. 1604 - 1606 (1981)

-

Efficient Synthesis of 2-Methyl-1-cyclopentene-1-carboxylic Acid

Harding, Kenn E.,Clement, Katherine S.,Gilbert, John C.,Wiechman, Barry

, p. 2049 - 2050 (1984)

-

Iridium complex-catalyzed addition of water and alcohols to non-activated terminal alkynes

Hirabayashi, Tomotaka,Okimoto, Yoshio,Saito, Akiyo,Morita, Masao,Sakaguchi, Satoshi,Ishii, Yasutaka

, p. 2231 - 2234 (2007/10/03)

The addition of water and alcohols to non-activated terminal alkynes was found to be promoted by an iridium complex combined with Lewis acid and phosphite. Thus, terminal alkynes reacted with water or alcohols to give ketones or ketals, respectively, in good to excellent yields. α,ω-Diyne like 1,7-octadiyne was converted into 1-(2-methyl-cyclopent-1-enyl)ethanone through the intramoleculer aldol condensation of the resulting 2,7-octanedione induced by Lewis acid.

Stereoselective construction of the dicyelopenta[a,d]cyclooctene core of the ceroplastin sesterterpenes by way of the anionic oxy-cope rearrangement

Paquette, Leo A.,Liang, Shaowo,Wang, Hui-Ling

, p. 3268 - 3279 (2007/10/03)

Bicyclo[3.2.1]oetanediones such as 9, which are readily available by double carbonylation of (1,3-cyclohexadiene)iron tricarbonyl complexes according to Eilbracht, are amenable to regiospecific methylenation under Wittig conditions. Reduction of 10 with copper hydride leads to 11, which can be resolved by application of Johnson's sulfoximine technology and oxidized to give the enantiopure antipodes of 10. Variously substituted cyclopentenyl anions undergo 1,2-addition to 10, providing carbinols which are capable of anionic oxy-Cope rearrangement via chair transition states. These structural reorganizations are fully stereocontrolled and lead directly to functionalized dicyclopenta[a,d]cyclooctenes. When 11 is treated analogously, only [1,3] sigmatropy is observed and inversion of stereochemistry at the migrating carbon prevails. Both processes exhibit impressive scaffolding powers and are characterized by brevity.

Hydration of Alkynes in Anhydrous Medium with Formic Acis as Water Donor

Menashe, Naim,Shvo, Youval

, p. 7434 - 7439 (2007/10/02)

Formic acid has been found to hydrate alkynes in the absence of water to give oxo products and carbon monoxide.The scope of the reaction of alkynes and formic acid has been delineated.Hydrocarbon alkynes were found to be reactive in the absence of catalyst.Functionalized alkynes, in particular oxygenated alkynes, are inert toward formic acid but can be activated catalytically with Ru3(CO)12.Consequently, all the tested types of alkynes were found to give oxo products and CO with formic acid.The mechanism of the reaction was examined.With some alkynes, the primary oxo products underwent secondary reactions that gave rise to unexpected products.

Process route upstream and downstream products

Process route

CH<sub>3</sub>COCH<sub>2</sub>CH<sub>2</sub>CH<sub>2</sub>CCMe
24395-06-0

CH3COCH2CH2CH2CCMe

2,3-dimethylcyclohex-2-en-1-one
1122-20-9

2,3-dimethylcyclohex-2-en-1-one

1-(2-methylcyclopent-1-enyl)ethanone
3168-90-9

1-(2-methylcyclopent-1-enyl)ethanone

Conditions
Conditions Yield
hydrogenchloride; In ethanol; at 60 ℃; for 144h; Mechanism; BF3 catalyzed cyclisation, also with HCl/H218O;
41.5%
hydrogenchloride; In ethanol; at 60 ℃; for 144h;
41.5%
hydrogenchloride; In ethanol; at 60 ℃; for 72h;
1-methylcyclopent-1-ene
693-89-0

1-methylcyclopent-1-ene

acetic anhydride
108-24-7

acetic anhydride

1-(2-methylcyclopent-1-enyl)ethanone
3168-90-9

1-(2-methylcyclopent-1-enyl)ethanone

1-[2-methyl-2-cyclopenten-1-yl]ethanone
64701-62-8,1767-84-6

1-[2-methyl-2-cyclopenten-1-yl]ethanone

Conditions
Conditions Yield
With zinc(II) chloride; at 10 - 15 ℃; for 10h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
acetic anhydride
108-24-7

acetic anhydride

1-(2-methylcyclopent-1-enyl)ethanone
3168-90-9

1-(2-methylcyclopent-1-enyl)ethanone

1-[2-methyl-2-cyclopenten-1-yl]ethanone
64701-62-8,1767-84-6

1-[2-methyl-2-cyclopenten-1-yl]ethanone

2-Acetyl-1-methyl-1-acetoxycyclopentane
109703-62-0

2-Acetyl-1-methyl-1-acetoxycyclopentane

Conditions
Conditions Yield
With zinc(II) chloride; at 0 ℃; for 2h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
2,7-octanedione
1626-09-1

2,7-octanedione

1-(2-methylcyclopent-1-enyl)ethanone
3168-90-9

1-(2-methylcyclopent-1-enyl)ethanone

1-[2-methyl-2-cyclopenten-1-yl]ethanone
64701-62-8,1767-84-6

1-[2-methyl-2-cyclopenten-1-yl]ethanone

Conditions
Conditions Yield
With potassium hydroxide; In ethanol; Heating;
1-methylcyclopent-1-ene
693-89-0

1-methylcyclopent-1-ene

acetic anhydride
108-24-7

acetic anhydride

1-(2-methylcyclopent-1-enyl)ethanone
3168-90-9

1-(2-methylcyclopent-1-enyl)ethanone

1-[2-methyl-2-cyclopenten-1-yl]ethanone
64701-62-8,1767-84-6

1-[2-methyl-2-cyclopenten-1-yl]ethanone

Acetic acid (1R,2R)-2-acetyl-1-methyl-cyclopentyl ester
80404-65-5,109703-62-0

Acetic acid (1R,2R)-2-acetyl-1-methyl-cyclopentyl ester

Conditions
Conditions Yield
With zinc(II) iodide; zinc(II) chloride; Yield given. Multistep reaction. Yields of byproduct given; 1.) 0 deg C, 15 min, 2.) 0 deg C, 2 h;
2,7-octanedione
1626-09-1

2,7-octanedione

1-(2-methylcyclopent-1-enyl)ethanone
3168-90-9

1-(2-methylcyclopent-1-enyl)ethanone

Conditions
Conditions Yield
With toluene-4-sulfonic acid; at 60 - 80 ℃; for 0.25h; under 0.0150015 Torr;
57%
With sulfuric acid;
With potassium hydroxide; ethanol;
With ethanol; potassium ethoxide;
With potassium carbonate;
With hydrogen cation;
With potassium hydroxide; In ethanol; Heating;
oct-1-yn-7-one
16737-04-5

oct-1-yn-7-one

1-(2-methylcyclopent-1-enyl)ethanone
3168-90-9

1-(2-methylcyclopent-1-enyl)ethanone

Conditions
Conditions Yield
With mercury dichloride; In neat (no solvent); at 50 ℃; for 40h; further support TiO2, ZrO2, silica gel, acidic, neutral, basic alumina;
81%
toluene-4-sulfonic acid; mercury dichloride; In diethyl ether; at 70 ℃; for 24h;
78%
at 300 ℃;
Multi-step reaction with 2 steps
1: triethyl amine / dimethylformamide / 144 h / 120 - 130 °C
2: 1.) mercury (II) chloride, HMDS; 2.) sodium iodide, 20percent HCl / 1.) methylene chloride, 30 deg C, 0.5 h; 2.) water, -15 deg C, 3h
With hydrogenchloride; triethylamine; 1,1,1,3,3,3-hexamethyl-disilazane; sodium iodide; mercury dichloride; In N,N-dimethyl-formamide;
1,7-Octadiyne
871-84-1

1,7-Octadiyne

2,7-octanedione
1626-09-1

2,7-octanedione

1-(2-methylcyclopent-1-enyl)ethanone
3168-90-9

1-(2-methylcyclopent-1-enyl)ethanone

Conditions
Conditions Yield
With water; hafnium tetrachloride; butan-1-ol; [Ir(1,5-cyclooctadiene)2]PF6; triisopropyl phosphite; at 70 ℃; for 15h;
87%
5%
With gadolinium(III) chloride; water; butan-1-ol; [Ir(1,5-cyclooctadiene)2]PF6; triisopropyl phosphite; at 70 ℃; for 15h;
47%
34%
acetyl chloride
75-36-5

acetyl chloride

1-(2-methylcyclopent-1-enyl)ethanone
3168-90-9

1-(2-methylcyclopent-1-enyl)ethanone

Conditions
Conditions Yield
With aluminium trichloride; In chloroform; 1) 2h, reflux, 2) RT, 2 days,;
37%
cyclohexane; acetyl chloride; With aluminum (III) chloride; In chloroform; for 50h;
With potassium hydroxide; In methanol; chloroform; at 20 ℃; for 16h;
32%
With aluminium trichloride; water;
With aluminium trichloride; tetrachlorosilane;
With aluminium trichloride; titanium tetrachloride;
With aluminium trichloride; tin(IV) chloride;
With aluminium trichloride; acetone;
With potassium hydroxide; aluminium trichloride; Yield given. Multistep reaction; 1.) CHCl3, 2.) methanol;
3-acetyl-2-methyl-1-(trimethylsilyl)cyclopentene
77494-17-8

3-acetyl-2-methyl-1-(trimethylsilyl)cyclopentene

1-(2-methylcyclopent-1-enyl)ethanone
3168-90-9

1-(2-methylcyclopent-1-enyl)ethanone

Conditions
Conditions Yield
With hydrogen fluoride; In acetonitrile; at 25 ℃;

Global suppliers and manufacturers

Global( 2) Suppliers
  • Company Name
  • Business Type
  • Contact Tel
  • Emails
  • Main Products
  • Country
  • BOC Sciences
  • Business Type:Trading Company
  • Contact Tel:1-631-485-4226
  • Emails:sales@bocsci.com
  • Main Products:41
  • Country:United States
  • SAGECHEM LIMITED
  • Business Type:Lab/Research institutions
  • Contact Tel:+86-571-86818502
  • Emails:will@sagechem.com
  • Main Products:28
  • Country:China (Mainland)
close
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 3168-90-9
Post Buying Request Now
close
Remarks: The blank with*must be completed