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317-46-4

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317-46-4 Usage

Description

2-Fluoro-3-nitrobenzoic acid is a light yellow crystalline powder that serves as a crucial intermediate in the synthesis of various organic compounds, pharmaceuticals, agrochemicals, and dyes due to its unique chemical properties.

Uses

Used in Organic Synthesis:
2-Fluoro-3-nitrobenzoic acid is used as a key intermediate for the production of various organic compounds. Its fluorinated and nitro-substituted aromatic structure makes it a versatile building block in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-fluoro-3-nitrobenzoic acid is utilized as a starting material for the development of new drugs. Its unique chemical structure allows for the creation of novel therapeutic agents with potential applications in treating various diseases and medical conditions.
Used in Agrochemicals:
2-Fluoro-3-nitrobenzoic acid is employed as a vital component in the formulation of agrochemicals, such as pesticides and herbicides. Its chemical properties contribute to the effectiveness of these products in controlling pests and promoting crop growth.
Used in Dye Industry:
In the dye industry, 2-fluoro-3-nitrobenzoic acid is used as a raw material for the production of various dyes. Its light yellow crystalline form and chemical properties enable the creation of a wide range of colorants for use in different applications, including textiles, plastics, and printing inks.

Check Digit Verification of cas no

The CAS Registry Mumber 317-46-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,1 and 7 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 317-46:
(5*3)+(4*1)+(3*7)+(2*4)+(1*6)=54
54 % 10 = 4
So 317-46-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H4FNO4/c8-6-4(7(10)11)2-1-3-5(6)9(12)13/h1-3H,(H,10,11)

317-46-4 Well-known Company Product Price

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  • Alfa Aesar

  • (H63235)  2-Fluoro-3-nitrobenzoic acid, 97%   

  • 317-46-4

  • 1g

  • 322.0CNY

  • Detail
  • Alfa Aesar

  • (H63235)  2-Fluoro-3-nitrobenzoic acid, 97%   

  • 317-46-4

  • 5g

  • 1196.0CNY

  • Detail

317-46-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-FLUORO-3-NITROBENZOIC ACID

1.2 Other means of identification

Product number -
Other names 2-Fluoro-3-nitrobenzoic acid+B244

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:317-46-4 SDS

317-46-4Downstream Products

317-46-4Relevant articles and documents

Synthesis method of 2-fluoro-3-nitrobenzoic acid intermediate raw material

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Paragraph 0024; 0034-0038; 0048-0052; 0062-0066; 0076-0080, (2021/06/26)

The invention discloses a synthesis method of a 2-fluoro-3-nitrobenzoic acid intermediate raw material. The invention provides a novel synthesis route, and an important medical intermediate can be rapidly and conveniently prepared from cheap and easily available raw materials. The process method comprises the following steps: starting from o-methylphenol, carrying out nitration reaction to selectively generate a key intermediate 2-methyl-6-nitrophenol, carrying out hydroxyl chlorination to generate 2-chloro-3-nitrotoluene, then carrying out fluorination reaction to generate 2-fluoro-3-nitrotoluene, and finally oxidizing methyl under the action of an oxidant to generate 2-fluoro-3-nitrobenzoic acid. The method is not only high in yield, but also suitable for large-scale production.

IMINOTETRAHYDROPYRIMIDINONE DERIVATIVES AS PLASMEPSIN V INHIBITORS

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Page/Page column 62, (2017/07/05)

A series of 2-imino-6-methyltetrahydropyrimidin-4(lH)-one derivatives, substituted in the 6-position by a phenyl moiety which in turn is meta-substituted by an optionally substituted unsaturated fused bicyclic ring system containing at least one nitrogen atom, being selective inhibitors of plasmepsin V activity, are beneficial as pharmaceutical agents, especially in the treatment of malaria.

COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR

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Page/Page column 152, (2011/07/09)

Compounds and salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof and uses thereof are described. In certain aspects and embodiments, the described compounds or salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof are active on each of B-Raf, B-Raf V600E and c-Raf-1 protein kinase. In certain aspects and embodiments, the described compounds are active in inhibiting proliferation of a Ras mutant cell line. Also described are methods of use thereof to treat diseases and conditions, including melanoma, glioma, glioblastoma, pilocytic astrocytoma, liver cancer, biliary tract cancer, cholangiocarcinoma, colorectal cancer, lung cancer, bladder cancer, gallbladder cancer, breast cancer, pancreatic cancer, thyroid cancer, kidney cancer, ovarian cancer, adrenocortical cancer, prostate cancer, gastrointestinal stromal tumors, medullary thyroid cancer, tumor angiogenesis, acute myeloid leukemia, chronic myelomonocytic leukemia, childhood acute lymphoblastic leukemia, plasma cell leukemia, and multiple myeloma.

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