31992-43-5

Basic information

• Product Name: 1-(3-AMINOPHENYL)PYRROLIDIN-2-ONE
• Synonyms: 1-(3-aminophenyl)pyrrolidin-2-one(SALTDATA: FREE);1-(3-aminophenyl)-2-pyrrolidone
• CAS NO: 31992-43-5
• Molecular Formula: C₁₀H₁₂N₂O
• Molecular Weight: 176.22
• Mol File: 31992-43-5.mol

Chemical Properties

• Melting Point: 105-107 °C(Solv: benzene (71-43-2))
• Boiling Point: 464.5°C at 760 mmHg
• Flash Point: 234.7°C
• Appearance: /
• Density: 1.234g/cm³
• Vapor Pressure: 8.34E-09mmHg at 25°C
• Refractive Index: 1.63
• PKA: 4.22±0.10(Predicted)
• CAS DataBase Reference: 1-(3-AMINOPHENYL)PYRROLIDIN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-AMINOPHENYL)PYRROLIDIN-2-ONE(31992-43-5)
• EPA Substance Registry System: 1-(3-AMINOPHENYL)PYRROLIDIN-2-ONE(31992-43-5)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 31992-43-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-(3-Aminophenyl)pyrrolidin-2-one is used as a building block for the synthesis of various biologically active compounds due to its versatile chemical structure and potential to be modified for specific therapeutic effects.
Used in Antidepressant and Anxiolytic Development:
1-(3-Aminophenyl)pyrrolidin-2-one is used as a potential antidepressant and anxiolytic agent, leveraging its capacity to modulate neurotransmitter systems involved in mood regulation and anxiety disorders.
Used in Pain and Inflammation Treatment:
1-(3-Aminophenyl)pyrrolidin-2-one is used as an inhibitor of the enzyme fatty acid amide hydrolase (FAAH), a target for treating pain and inflammation by affecting the endocannabinoid system, which plays a role in pain perception and modulation.
Used in Medicinal Chemistry Research and Development:
1-(3-Aminophenyl)pyrrolidin-2-one is utilized in the field of medicinal chemistry for further research and development, given its potential to contribute to the discovery of new drugs and therapeutic agents for various medical conditions.

InChI:InChI=1/C10H12N2O/c11-8-3-1-4-9(7-8)12-6-2-5-10(12)13/h1,3-4,7H,2,5-6,11H2

Upstream product

• 99-09-2 3-nitro-aniline 
• 585-79-5 m-nitrobromobenzene 
• 61372-79-0 1-(3-nitrophenyl)-2-oxotetrahydropyrrole 
• 96-48-0 4-butanolide 
• 108-45-2 m-phenylenediamine 

Downstream Products

• 329280-75-3 1-[3-(5-bromo-3-nitropyridin-2-ylamino)phenyl]pyrrolidin-2-one 
• 1190377-88-8 cyclobutanecarboxylic acid (3-{5-cyclopropyl-2-[3-(2-oxo-pyrrolidin-1-yl)-phenylamino]-pyrimidin-4-ylamino}-propyl)-amide 
• 1233206-32-0 3-[6-(3-(2-oxopyrrolidin-1-yl)phenylamino)pyridin-2-yl]pyrazolo[1,5-a]pyridine 
• 1443438-15-0 C₂₅H₂₃F₆N₃O₃ 
• 1401731-36-9 1-(3-((6-(3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)pyrazin-2-yl)amino)phenyl)pyrrolidin-2-one 
• 1401732-44-2 1-(3-((6-(1-(4-methoxybenzyl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)pyrazin-2-yl)amino)phenyl)pyrrolidin-2-one 
• 1401732-43-1 1-(3-((6-chloropyrazin-2-yl)amino)phenyl)pyrrolidin-2-one 
• 1215125-42-0 1-[3-({5-(Trifluoromethyl)-4-[(1,1,1-trifluoropropan-2-yl)amino]pyrimidin-2-yl}amino)phenyl]-pyrrolidin-2-one 
• 1215126-62-7 1-(3-{[4-chloro-5-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)pyrrolidin-2-one 
• 1257516-09-8 (E)-tert-butyl (tert-butoxycarbonylamino)(3-(2-oxopyrrolidin-1-yl)phenylamino)methylenecarbamate 
• 922926-09-8 N-(3-(2-oxopyrrolidin-1-yl)phenyl)cyclohexanecarboxamide 
• 1014949-96-2 N-(3-(2-oxopyrrolidin-1-yl)phenyl)cinnamamide 
• 922886-66-6 N-(3-(2-oxopyrrolidin-1-yl)phenyl)butyramide 
• 330657-69-7 N-(3-(2-oxopyrrolidin-1-yl)phenyl)benzamide 

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