33973-14-7

Basic information

• Product Name: 6-methoxy-2-phenyl-1-benzofuran
• Synonyms: 6-methoxy-2-phenyl-1-benzofuran
• CAS NO: 33973-14-7
• Molecular Weight: 224.259
• Mol File: 33973-14-7.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: 6-methoxy-2-phenyl-1-benzofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methoxy-2-phenyl-1-benzofuran(33973-14-7)
• EPA Substance Registry System: 6-methoxy-2-phenyl-1-benzofuran(33973-14-7)

Safety Data

• Hazardous Substances Data: 33973-14-7(Hazardous Substances Data)

Upstream product

• 673-22-3 2-Hydroxy-4-methoxybenzaldehyde 
• 2882-19-1 ethyl 2-phenyl-2-bromoacetate 
• 1018669-02-7 2-(2-hydroxy-4-methoxyphenyl)-1-phenyl-1-ethanone 
• 24845-40-7 2-(4-methoxyphenyl)acetophenone 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 106-51-4 p-benzoquinone 
• 37167-62-7 bromo-phenyl-acetic acid methyl ester 
• 41046-70-2 2-iodo-5-methoxyphenol 
• 536-74-3 phenylacetylene 
• 108639-46-9 1-(2,2-diethoxyethoxy)-3-methoxybenzene 
• 150-19-6 O-methylresorcine 
• 50551-63-8 6-methoxybenzofuran 
• 114-83-0 1-acetyl-2-phenylhydrazine 
• 103-54-8 cinnamyl acetate 

Downstream Products

• 120990-49-0 (6-hydroxy-2-phenyl-1-benzofuran-3-yl)(4-hydroxyphenyl)methanone 
• 120990-48-9 <6-methoxy-2-phenyl-1-benzofuran-3-yl>(4-methoxyphenyl)methanone 
• 24534-37-0 6-hydroxy-2-phenylbenzofuran 

Relevant articles and documents

The Ligand Free Palladium(II)-Catalyzed Regioselective 1,2-Addition of Enol Silanes to Quinones to Access 4-Hydroxy-4-(2-oxo-2-arylethyl)cyclohexadien-1-ones and Synthetic Applications

In contrast to the conventional 1,4-addition process, regioselective 1,2-addition of silyl enol ethers to quinones can now be achieved via a palladium(II) enolate pathway that provides access to 4-hydroxy-4-(2-oxo-2-arylethyl)cyclohexa-2,5-dien-1-one derivatives. This quinone alkylation protocol proceeds under mild reaction conditions at ambient temperature under open air and does not require either an external ligand for the palladium or the use of a base. Additionally, the cyclohexadienone products have been exploited as synthetic precursors for the construction of fused heteroaryl systems.

Synthesis and biological evaluation of 2-arylbenzofuran derivatives as potential anti-Alzheimer’s disease agents

Alzheimer's disease (AD) is a type of progressive dementia caused by degeneration of the nervous system. A single target drug usually does not work well. Therefore, multi-target drugs are designed and developed so that one drug can specifically bind to mu

CuI catalyzed domino coupling–cyclization of 2-iodo-phenols and 1-alkynes to the synthesis of 2-substituted benzo[b]furans/furo-pyridines

CuI/proline-catalyzed coupling reaction of 2-iodo-phenols with terminal alkynes and the following cyclization process is carried out successively in DMSO at 80 °C. Under this tandem process, 2-substituted benzo[b]furans/furo-pyridines were synthesized in good to excellent yields with a great diversity.