37920-25-5

Basic information

• Product Name: 1-(4-Butylphenyl)ethan-1-one
• Synonyms: 1-(4-butylphenyl)-ethanon;Ethanone, 1-(4-butylphenyl)-;P-BUTYLACETOPHENONE;LABOTEST-BB LT00159031;1-(4-BUTYL-PHENYL)ETHANONE;1-(4-BUTYLPHENYL)ETHAN-1-ONE;4'-N-BUTYLACETOPHENONE;4-N-BUTYLACETOPHENONE
• CAS NO: 37920-25-5
• Molecular Formula: C₁₂H₁₆O
• Molecular Weight: 176.25
• EINECS: 253-715-7
• Product Categories: Aromatic Acetophenones & Derivatives (substituted);Phenyls & Phenyl-Het;Acetophenones (Building Blocks for Liquid Crystals);Building Blocks for Liquid Crystals;Functional Materials;Phenyls & Phenyl-Het;C11 to C12;Carbonyl Compounds;Ketones;Building Blocks;C11 to C12;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks
• Mol File: 37920-25-5.mol
• Article Data: 61

Chemical Properties

• Boiling Point: 101-102 °C1.5 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: Clear colorless to pale yellow/Liquid
• Density: 0.957 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00522mmHg at 25°C
• Refractive Index: 1.5170-1.5220
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform, Ethyl Acetate (Slightly)
• Water Solubility: Not miscible in water.
• CAS DataBase Reference: 1-(4-Butylphenyl)ethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Butylphenyl)ethan-1-one(37920-25-5)
• EPA Substance Registry System: 1-(4-Butylphenyl)ethan-1-one(37920-25-5)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22-36/37/38
• Safety Statements: 23-26-36/37/39
• WGK Germany: 3
• TSCA: Yes
• HazardClass: IRRITANT
• Hazardous Substances Data: 37920-25-5(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 37920-25-5 differently. You can refer to the following data:
1. Intermediates of Liquid Crystals
2. 4'-n-Butylacetophenone is used as an organic chemical synthesis intermediate.

InChI:InChI=1/C12H16O/c1-3-4-5-11-6-8-12(9-7-11)10(2)13/h6-9H,3-5H2,1-2H3

Upstream product

• 104-51-8 1-butylbenzene 
• 75-36-5 acetyl chloride 
• 7446-70-0 aluminium trichloride 
• 123-86-4 acetic acid butyl ester 
• 71-43-2 benzene 
• 99-90-1 para-bromoacetophenone 
• 15676-66-1 tri-n-butylindium 
• 109-72-8 n-butyllithium 
• 6638-68-2 4,5-dimethyl-2-phenyl-1,3,2-dioxaborolane 
• 69497-83-2 4-acetylphenyl mesylate 
• 13329-40-3 4-Iodoacetophenone 
• 201230-82-2 carbon monoxide 
• 109-65-9 1-bromo-butane 
• 26206-42-8 1-butyl-4-vinylbenzene 

Downstream Products

• 125639-56-7 1-(n-butylphenyl)ethyl alcohol 
• 618068-97-6 4-[5-(4-butylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide 
• 109777-27-7 4,4,4-trifluoro-1-(4-butylphenyl)butane-1,3-dione 
• 1605320-63-5 tetramethyl 2-(4-butylbenzoyl)propane-1,1,3,3-tetracarboxylate 
• 1359983-61-1 4-(4-butylphenyl)-1H-imidazol-2-amine hydrochloride 
• 1359983-79-1 C₁₈H₂₅N₃O₂ 
• 1332887-32-7 1-(4-acetylphenyl)butyl nitrate 
• 1235999-49-1 1-(4-acetyl-phenyl)-butan-1-one 
• 852815-58-8 ethyl 4-(4-butylphenyl)-2,4-dioxobutanoate 
• 168832-61-9 1-(1-n-butyl-2-methylindol-3-yl)-1-(4-n-butylphenyl)ethylene 
• 94775-60-7 Potassium; 2-[2-(4-butyl-phenyl)-1-hydroxy-2-oxo-ethyl]-3-oxo-hexanoate 
• 94775-69-6 1-(4-Butyl-phenyl)-2-hydroxy-heptane-1,4-dione 
• 94775-78-7 3-(4-Butyl-phenyl)-6-propyl-pyridazine 
• 106793-09-3 6-(4-Butyl-phenyl)-2-chloro-nicotinonitrile 

Relevant articles and documents

Unprecedented nucleophilic addition of organolithiums to aromatic aldehydes and ketones by complexation with aluminum tris(2,6-diphenylphenoxide)

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Scalable Negishi Coupling between Organozinc Compounds and (Hetero)Aryl Bromides under Aerobic Conditions when using Bulk Water or Deep Eutectic Solvents with no Additional Ligands

Pd-catalyzed Negishi cross-coupling reactions between organozinc compounds and (hetero)aryl bromides have been reported when using bulk water as the reaction medium in the presence of NaCl or the biodegradable choline chloride/urea eutectic mixture. Both C(sp3)-C(sp2) and C(sp2)-C(sp2) couplings have been found to proceed smoothly, with high chemoselectivity, under mild conditions (room temperature or 60 °C) in air, and in competition with protonolysis. Additional benefits include very short reaction times (20 s), good to excellent yields (up to 98 %), wide substrate scope, and the tolerance of a variety of functional groups. The proposed novel protocol is scalable, and the practicability of the method is further highlighted by an easy recycling of both the catalyst and the eutectic mixture or water.

Generation of Alkyl Radical through Direct Excitation of Boracene-Based Alkylborate

The generation of tertiary, secondary, and primary alkyl radicals has been achieved by the direct visible-light excitation of a boracene-based alkylborate. This system is based on the photophysical properties of the organoboron molecule. The protocol is applicable to decyanoalkylation, Giese addition, and nickel-catalyzed carbon-carbon bond formations such as alkyl-aryl cross-coupling or vicinal alkylarylation of alkenes, enabling the introduction of various C(sp3) fragments to organic molecules.