383-70-0

Basic information

• Product Name: N-(Trifluoroacetyl)glycine
• Synonyms: TRIFLUOROACETYL GLYCINE;n-(trifluoroacetyl)glycine;N-ALPHA-TRIFLUOROACETYL-GLYCINE;TFA-GLYCINE;TFA-GLY-OH;[(Trifluoroacetyl)amino]acetic acid;glycine,N-(trifluoroacetyl)-;N-alpha-Trifluoracetyl-glycin
• CAS NO: 383-70-0
• Molecular Formula: C₄H₄F₃NO₃
• Molecular Weight: 171.07
• Product Categories: Amino Acids;Amino Acids 13C, 2H, 15N;Amino Acids & Derivatives
• Mol File: 383-70-0.mol

Chemical Properties

• Melting Point: 120-121 °C
• Boiling Point: 291.6°C
• Flash Point: 130°C
• Appearance: white solid
• Density: 1.534
• Vapor Pressure: 0.000479mmHg at 25°C
• Refractive Index: 1.386
• Storage Temp.: 2-8°C
• Solubility: Chloroform, DMSO
• PKA: 2.99±0.10(Predicted)
• CAS DataBase Reference: N-(Trifluoroacetyl)glycine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(Trifluoroacetyl)glycine(383-70-0)
• EPA Substance Registry System: N-(Trifluoroacetyl)glycine(383-70-0)

Safety Data

• Hazardous Substances Data: 383-70-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
N-(Trifluoroacetyl)glycine is used as a synthetic building block for the creation of a wide range of organic compounds. Its application in this field is due to its ability to participate in various chemical reactions, such as condensation, substitution, and rearrangement, which are essential for the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N-(Trifluoroacetyl)glycine is used as an intermediate in the synthesis of various drugs and drug candidates. Its unique chemical properties allow it to be a key component in the development of new medications, contributing to the advancement of pharmaceutical research and drug discovery.
Used in Chemical Research:
N-(Trifluoroacetyl)glycine is also employed as a research tool in the field of chemistry. It is used to study the properties and behavior of various chemical reactions, providing valuable insights into the mechanisms and pathways involved. This helps researchers to better understand the underlying principles of organic chemistry and to develop new strategies for the synthesis of complex molecules.
Used in Material Science:
In the field of material science, N-(Trifluoroacetyl)glycine is used as a component in the development of novel materials with specific properties. Its unique chemical structure allows it to be incorporated into the design of new materials, such as polymers, coatings, and composites, which can be tailored for various applications, including electronics, aerospace, and automotive industries.

InChI:InChI=1/C4H4F3NO3/c5-4(6,7)3(11)8-1-2(9)10/h1H2,(H,8,11)(H,9,10)

Upstream product

• 383-64-2 S-ethyl trifluoroacetate 
• 56-40-6 glycine 
• 500-73-2 phenyl trifluoroacetate 
• 407-25-0 trifluoroacetic anhydride 
• 354-32-5 trifluoracetyl chloride 
• 431-47-0 trifluoroacetic acid-methyl ester 
• 383-63-1 ethyl trifluoroacetate, 
• 848860-95-7 S-dodecyl trifluorothioacetate 

Downstream Products

• 2821-48-9 N-trifluoroacetyl-glycine-(N'-trityl-hydrazide) 
• 370-34-3 N-trifluoroacetyl-thioglycine S-phenyl ester 
• 370-33-2 N-trifluoroacetyl-glycine anilide 
• 785-71-7 N-trifluoroacetyl-glycine phenyl ester 
• 3397-30-6 2-(2,2,2-trifluoroacetamido)acetic acid succinimidyl ester 
• 752253-28-4 2,4,6-Triiodo-5-{methyl[2-(2,2,2-trifluoroacetylamino)-acetyl]amino}-isophthalic acid dichloride 
• 752253-20-6 2,4,6-triiodo-5-[2-(2,2,2-trifluoroacetylamino)-acetylamino]-isophthalic acid dichloride 
• 1275611-24-9 C₃₈H₃₅F₃N₄O₁₀ 
• 4554-41-0 N-trifluoroacetyl-glycinyl-L-phenylalanine methyl ester 
• 1599422-98-6 N-(trifluoroacetyl)glycine {N-benzyl-N-[4-tert-butyldimethylsilyloxy-(2E)-buten-1-yl]}amide 
• 82706-23-8 (E)-But-2-en-1-yl 2-(2,2,2-trifluoroacetamido)acetate 
• 1301701-44-9 (E)-2-phenylbut-2-enyl 2-(2,2,2-trifluoroacetamido)acetate 
• 1202396-37-9 C₃₀H₃₅F₃N₂O₇ 
• 1202396-35-7 C₃₀H₂₈ClF₃N₂O₇ 

Relevant articles and documents

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