38791-02-5Relevant articles and documents
One-pot synthesis of 5-phenylsulfonyl-3-aroylisoxazolines and 3-aroylisoxazoles from alkynes and (phenylsulfonyl)ethene
Wang, Liang,Zhang, Nana
, p. 390 - 392 (2021/06/07)
Iron(III) nitrate-assisted cycloaddition of (phenylsulfonyl)ethene to arylacetylenes in the presence of KI affords 5-phenylsulfonyl-3-aroylisoxazolines whose treatment with K2CO3 provides 4,5-unsubstituted 3-aroylisoxazoles. Both synthetic steps can be performed in a one-pot manner.
3-acyl isoxazole compound and preparation method thereof
-
, (2020/12/15)
The invention discloses a 3acyl isoxazole compound and a preparation method thereof. The No.4 and No.5 positions of the 3acyl isoxazole compound are free of substituent groups, and subsequent functionalization is facilitated according to use requirements, so that the structure type of the 3acyl isoxazole compound is expanded, and the 3acyl isoxazole compound has potential application value. According to the method for preparing the 3acyl isoxazole compound, the ketone compound, phenyl vinyl sulfone and tert-butyl nitrite are used as reaction raw materials; an aqueous solution containing a surfactant is used as a reaction solvent; the 3acyl isoxazole compound is synthesized through a two-step reaction; and no metal catalyst is needed in a reaction process, namely, the 3acyl isoxazole compound is synthesized in a mild and green reaction environment, the selectivity and yield of the product are very high, the application range of the ketone compound is wide. The method has a good amplified synthesis prospect.
Reactions of Acetylenic Hydrocarbons with Dimedone and Some α-Nitroketones
Dybova,Yurchenko,Gritsai,Komarov
, p. 642 - 646 (2007/10/03)
Vinylation of acetylene and phenylacetylene with dimedone in the presence of catalytic amounts of sulfuric acid is accompanied by addition of the second dimedone molecule, followed by intramolecular cyclization in the case of phenylacetylene. Reactions of