39794-75-7

Basic information

• Product Name: Ethyl (p-tosyloxy)acetate
• Synonyms: Acetic acid, [[(4-methylphenyl)-sulfonyl]oxy]-, ethyl ester;Ethyl (p-tosyloxy)acetate;Tosylethylglycolate;Ethyl 2-(p-Toluenesulfonyloxy)acetate;2-(p-Toluenesulfonyloxy)acetic Acid Ethyl Ester;ethyl 2-(tosyloxy)acetate;Ethyl 2-(p-Toluenesulfonyloxy)acetate;(Toluene-4-sulfonyloxy)-acetic acid ethyl ester
• CAS NO: 39794-75-7
• Molecular Formula: C₁₁H₁₄O₅S
• Molecular Weight: 258.29
• Mol File: 39794-75-7.mol
• Article Data: 7

Chemical Properties

• Melting Point: 45.0 to 49.0 °C
• Boiling Point: 171-174 °C(Press: 2 Torr)
• Appearance: /
• Density: 1.248±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Ethyl (p-tosyloxy)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl (p-tosyloxy)acetate(39794-75-7)
• EPA Substance Registry System: Ethyl (p-tosyloxy)acetate(39794-75-7)

Safety Data

• Hazardous Substances Data: 39794-75-7(Hazardous Substances Data)

Usage

Chemical Properties

Colourless solid

Uses

(Toluene-4-sulfonyloxy)-acetic acid ethyl ester (cas# 39794-75-7) is an intermediate in the synthesis of Tosylglycolic Acid (T664020), an intermediate of Cefmetazole (C242850).

Upstream product

• 623-50-7 ethyl 2-hydroxyacetate 
• 98-59-9 p-toluenesulfonyl chloride 
• 623-73-4 diazoacetic acid ethyl ester 
• 104-15-4 toluene-4-sulfonic acid 
• 64-17-5 ethanol 
• 109-99-9 tetrahydrofuran 
• 503-68-4 diazoacetic acid 

Downstream Products

• 158818-29-2 N-phenyl-O-tosylglycolamide 
• 501919-59-1 2-hydroxy-4-[[2-[[(4-methylphenyl)sulfonyl]oxy]acetyl]amino]benzoic acid 
• 959119-78-9 4-(2-(tosyloxy)acetamido)benzoic acid 
• 82187-66-4 ethyl 2-(thiophen-2-sulfanyl)acetate 
• 75032-27-8 ethyl <(p-nitrophenyl)thio>acetate 
• 14738-27-3 ethyl (p-tolylthio)acetate 
• 78066-05-4 ethyl 2-(p-fluorophenylthiaoxy)acetate 
• 1334484-14-8 2-((2,5-dimethoxybenzyl)(2-phenoxyphenyl)amino)-2-oxoethyl-4-methylbenzenesulfonate 
• 39794-77-9 2-(4-methylphenyl)sulfonyloxyacetic acid 
• 16124-65-5 [4-(4-Nitro-phenylamino)-phenoxy]-acetic acid ethyl ester 
• 6975-17-3 ethyl 1-oxaspiro[2.5]octane-2-carboxylate 

Relevant articles and documents

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Synthesis of thioether andrographolide derivatives and their inhibitory effect against cancer cells

A series of novel thioether andrographolide derivatives were synthesized by incorporating various aromatic (or heteroaromatic) substituents into C-12 or 14-OH. A total of 38 andrographolide derivatives were prepared and evaluated for their in vitro inhibi

Synthesis of [11C]PBR06 and [18F]PBR06 as agents for positron emission tomographic (PET) imaging of the translocator protein (TSPO)

The translocator protein 18 kDa (TSPO) is an attractive target for molecular imaging of neuroinflammation and tumor progression. [ 18F]PBR06, a fluorine-18 labeled form of PBR06, is a promising PET TSPO radioligand originally developed at NIMH.