403-43-0

Basic information

• Product Name: 4-Fluorobenzoyl chloride
• Synonyms: 4-fluoro-benzoylchlorid;Benzoyl chloride, p-fluoro-;para-Fluorobenzoyl chloride;p-Fluorobenzoic acid chloride;P-FLUOROBENZOYL CHLORIDE;FLUOROBENZOYL(4-) CHLORIDE;LABOTEST-BB LTBB000747;4-Fluorobenozylchloride
• CAS NO: 403-43-0
• Molecular Formula: C₇H₄ClFO
• Molecular Weight: 158.56
• EINECS: 206-961-4
• Product Categories: Benzene derivatives;Fluorobenzene;Acid Halides;Carbonyl Compounds;Organic Building Blocks;Carbonyl Compounds
• Mol File: 403-43-0.mol
• Article Data: 144

Chemical Properties

• Melting Point: 10-12 °C(lit.)
• Boiling Point: 82 °C20 mm Hg(lit.)
• Flash Point: 180 °F
• Appearance: Clear colorless to light yellow/Liquid
• Density: 1.342 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.000277mmHg at 25°C
• Refractive Index: n20/D 1.532(lit.)
• Storage Temp.: 2-8°C
• Water Solubility: Reacts with water.
• Sensitive: Lachrymatory
• BRN: 386215
• CAS DataBase Reference: 4-Fluorobenzoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Fluorobenzoyl chloride(403-43-0)
• EPA Substance Registry System: 4-Fluorobenzoyl chloride(403-43-0)

Safety Data

• Hazard Codes: C
• Statements: 34-36/37-14
• Safety Statements: 26-36/37/39-45-28A-27
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 3
• F: 10-19
• TSCA: T
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 403-43-0(Hazardous Substances Data)

Usage

Chemical Properties

clear colourless to light yellow liquid

Uses

It is used in the synthesis of polyphenylene ether and thioether ketones and also in the synthesis fluorinated poly(aryl ether ketone)s containing 1,4-naphthalene moieties. It is also used as a raw material in engineering of plastics.

General Description

4-Fluorobenzoyl chloride undergoes Friedel-Crafts acylation reaction with 2,6-dimethylnaphthalene to give 1,5-bis(4-fluorobenzoyl)-2,6-dimethylnaphthalene.

InChI:InChI=1/C6H4FNO2/c7-5-2-1-4(3-8-5)6(9)10/h1-3H,(H,9,10)

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 93342-79-1 1-(4-Fluoro-benzoyl)-3-methyl-3H-imidazol-1-ium; chloride 
• 456-22-4 4-Fluorobenzoic acid 
• 403-33-8 methyl 4-flurobenzoate 
• 24167-56-4 N,N-dimethyl-4-fluorobenzamide 
• 402-42-6 4-fluoro-1-trichloromethylbenzene 
• 13656-36-5 3,5-dichloro-2,4,6-trifluorobenzoic acid 
• 316142-60-6 N-(4-cyanophenyl)-4-fluorobenzamide 
• 707-74-4 (trichloromethyl)mesitylene 
• 352-34-1 4-fluoro-1-iodobenzene 
• 141-75-3 butyryl chloride 
• 14432-12-3 4-Amino-2-chloropyridine 
• 100-20-9 terephthaloyl chloride 
• 122-04-3 4-nitro-benzoyl chloride 

Downstream Products

• 325-98-4 4-fluoro-N-(pyrimidin-2-yl)benzamide 
• 93669-28-4 N-(3-(1H-imidazol-1-yl)propyl)-4-fluorobenzamide 
• 87539-74-0 6-Chloro-3-(4-fluoro-phenyl)-[1,2,4]triazolo[3,4-a]phthalazine 
• 129227-31-2 1-(4-fluorophenyl)-[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one 
• 4146-56-9 4-fluoro-benzoic acid-(2-piperidino-ethyl ester) 
• 2561-29-7 6-(4-fluoro-benzoylamino)-benzo[1,3]dioxole-5-carboxylic acid methyl ester 
• 129696-75-9 4-Fluoro-benzoic acid 6-acetyl-2-cyano-3,4-dimethyl-phenyl ester 
• 96898-35-0 5-(4-fluorophenyl)-3-(4-nitrophenyl)-1,2,4-oxadiazole 
• 85210-64-6 N-(4-fluorobenzoyl)-N-[(thien-2-ylcarbonyl)methyl]amine 
• 88352-93-6 N-(4-fluorobenzoyl)-(furan-2-ylcarbonyl)methylamine 
• 49684-66-4 (4-fluorobenzoyl)(pyridin-1-ium-1-yl)amide 
• 2054-00-4 4-fluoro-N-[3-(trifluoromethyl)phenyl]benzamide 
• 134279-85-9 C₁₅H₁₆ClFN₃O₃ 
• 67516-51-2 5-(4-fluoro-benzoylamino)-pyridine-2-carboxylic acid methyl ester 

Relevant articles and documents

Branched-arm macromolecule liquid crystals-containing fluorine and isosorbide-structure and properties

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Pine Rosin as a Valuable Natural Resource in the Synthesis of Fungicide Candidates for Controlling Fusarium oxysporum on Cucumber

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