41738-70-9

Basic information

• Product Name: 3-Bromo-biphenyl-4-ylamine
• Synonyms: 3-bromo-4-phenylaniline;3-Bromo-biphenyl-4-ylamine;3-bromobiphenyl-4-amine;3-bromo-[1,1-biphenyl]-4-amine
• CAS NO: 41738-70-9
• Molecular Formula: C₁₂H₁₀BrN
• Molecular Weight: 248.1185
• Mol File: 41738-70-9.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 332.4°Cat760mmHg
• Flash Point: 154.8°C
• Appearance: /
• Density: 1.432g/cm³
• Vapor Pressure: 0.000146mmHg at 25°C
• Refractive Index: 1.644
• CAS DataBase Reference: 3-Bromo-biphenyl-4-ylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-biphenyl-4-ylamine(41738-70-9)
• EPA Substance Registry System: 3-Bromo-biphenyl-4-ylamine(41738-70-9)

Safety Data

• Hazardous Substances Data: 41738-70-9(Hazardous Substances Data)

Usage

General Description

3-Bromo-biphenyl-4-ylamine, also known as 3-Bromo-4-aminobiphenyl, is a chemical compound that consists of a biphenyl ring with a bromine atom and an amino group attached at the 3 and 4 positions, respectively. 3-Bromo-biphenyl-4-ylamine is commonly used as a building block in the synthesis of various organic compounds and pharmaceuticals. It is also used as a key intermediate in the production of dyes, pigments, and other specialty chemicals. Additionally, 3-Bromo-biphenyl-4-ylamine is known for its role in the field of medicinal chemistry, where it is utilized in the development of potential drug candidates for the treatment of various diseases and conditions. Overall, this chemical plays an important role in the fields of organic synthesis, chemical manufacturing, and pharmaceutical research.

InChI:InChI=1/C12H10BrN/c13-11-8-10(6-7-12(11)14)9-4-2-1-3-5-9/h1-8H,14H2

Upstream product

• 615-57-6 2,4-dibromo-aniline 
• 98-80-6 phenylboronic acid 
• 100-58-3 phenylmagnesium bromide 
• 540-37-4 p-aminoiodobenzene 
• 4075-79-0 4-phenylacetanilide 
• 92-67-1 4-phenylalanine 
• 39224-23-2 4-acetamido-3-bromobiphenyl 
• 1439-12-9 N-bromo-acetanilide 
• 67-66-3 chloroform 

Downstream Products

• 900806-53-3 3-bromo-4-iodo-[1,1']biphenyl 
• 103012-26-6 3-phenyl-9H-carbazole 
• 1453098-05-9 2-phenyl-6-(trifluoromethyl)phenanthridine 

Relevant articles and documents

Organic compound and organic electroluminescent device containing the same

The invention relates to an organic compound, which is characterized by having a structure as shown in (1) in the specification, wherein X is selected from O or S; L is selected from a single bond, a substituted or unsubstituted C6-C30 arylene group or C3

Selective Thiocyanation and Aromatic Amination to Achieve Organized Annulation of Enaminone with Thiocyanate

A tandem insertion of thiocyanate to enamine was performed for the regioselective synthesis of multisubstituted benzoimidazo[2,1-b]thiazoles. This method was shown to be effective in addressing the issue of isomerization encountered in common strategies. With a change made to the leading group on the aniline fragment of enamine, the reaction achieved different transformations, thus enabling multisubstituted benzo[4,5]imidazo[2,1-b]thiazoles and thiazoles in satisfactory yields.

Palladium-catalysed room-temperature Suzuki–Miyaura coupling in water extract of pomegranate ash, a bio-derived sustainable and renewable medium

An agro waste-derived, ‘water extract of pomegranate ash’ (WEPA), has been utilized for the first time as a renewable medium for Pd(OAc)2-catalysed Suzuki–Miyaura cross-coupling at room temperature. This method offers a simple and sustainable synthesis of biaryls from aryl halides and arylboronic acids under ligand- and external base-free aerobic and ambient conditions. This method has been found effective for both activated and unactivated aryl halides in the production of biaryls with moderate to nearly quantitative yields. The protocol shows high chemoselectivity over identical/similar reactive sites in aryl halides (i.e. selectivity over identical halogens or different halogens of aryl halides). This method exhibits high regioselectivity, i.e. the selective reactivity of a halogen over other identical halogens at different positions on the aromatic nucleus. Therefore, we disclose here a clean, benign, substantial chemo- and regioselective and highly economic alternative method for the palladium-assisted synthesis of biaryls using an agro waste-derived medium.