4519-39-5

Basic information

• Product Name: 2,3-Difluorobenzoic acid
• Synonyms: 2,3-DIFLUOROBENZOIC ACID;CHEMPACIFIC 39931;BUTTPARK 45\01-40;TIMTEC-BB SBB006679;RARECHEM AL BO 0251;2,3-Difluorobenzoicacid,98%;2,3-Difluorobenzoic;2,3-Difluorobenzoic acid 98%
• CAS NO: 4519-39-5
• Molecular Formula: C₇H₄F₂O₂
• Molecular Weight: 158.1
• Product Categories: Fluorin-contained Benzoic acid series;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Aromatic compound;Benzoic acid;Fluorobenzene;Miscellaneous;C7;Carbonyl Compounds;Carboxylic Acids;Fluorine series;Pyrroles
• Mol File: 4519-39-5.mol
• Article Data: 4

Chemical Properties

• Melting Point: 163-165 °C(lit.)
• Boiling Point: 248.1 °C at 760 mmHg
• Flash Point: 103.9 °C
• Appearance: white to off-white powder
• Density: 1.3486 (estimate)
• Vapor Pressure: 0.0131mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.93±0.10(Predicted)
• Water Solubility: slightly soluble
• BRN: 2640781
• CAS DataBase Reference: 2,3-Difluorobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Difluorobenzoic acid(4519-39-5)
• EPA Substance Registry System: 2,3-Difluorobenzoic acid(4519-39-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-37/38-36
• Safety Statements: 26-37/39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 4519-39-5(Hazardous Substances Data)

Usage

Chemical Properties

white to off-white powder

Uses

2,3-Difluorobenzoic acid has been used as a tracer for determining the extent of recovery of materials injected into oil wells.

General Description

2,3-Difluorobenzoic acid forms dimers that are stabilized by hydrogen bonds.

InChI:InChI=1/C7H4F2O2/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3H,(H,10,11)/p-1

Upstream product

• 65-85-0 benzoic acid 
• 124-38-9 carbon dioxide 
• 367-11-3 ortho-difluorobenzene 
• 126163-64-2 lithium 2,3-difluorobenzene 
• 1489-53-8 1,2,3-trifluorobenzene 
• 2646-91-5 2,3-difluorobenzaldehyde 
• 61079-72-9 2,3,4,-trifluorobenzoic acid 

Downstream Products

• 18355-73-2 2,3-difluorobenzoyl chloride 
• 129589-65-7 1-(tert-butoxycarbonylamino)-2,3-difluorobenzene 
• 230628-49-6 5-chloro-6-(2,3-difluoro-benzoyl)-3H-benzooxazol-2-one 
• 847972-30-9 5-(chlorosulfonyl)-2,3-difluorobenzoic acid 
• 858939-32-9 2-(2,3-difluorophenyl)-7-methyl-1⁽³⁾H-imidazo[4,5-c]pyridine 
• 858935-15-6 2-(2,3-difluorophenyl)-1⁽³⁾H-imidazo[4,5-c]pyridine 
• 333780-74-8 2,3-difluoro-5-iodobenzoic acid 
• 223444-56-2 2,3-difluoro-N-(tert-butyl)benzamide 
• 147696-82-0 4'-Amino-2,3-difluorobenzophenone 
• 1105062-83-6 6-(2,3-difluoro-phenyl)-2H-imidazo[4,5-c]pyridazine 

Relevant articles and documents

Preparation method of 2,3-difluorobenzoic acid

The invention discloses a preparation method of 2,3-difluorobenzoic acid and belongs to the field of organic chemical synthesis. The method comprises the following steps: taking o-difluoro benzene, carrying out substitution reaction to obtain 2,3-difluorobenzene lithium, then carrying out addition reaction to obtain 2,3-difluorobenzoic acid. Through the preparation method of 2,3-difluorobenzoic acid, the production cost is reduced; the pollution to the environment is reduced; the purity and the yield of the product are improved; and the preparation method has the advantages of easily availableraw materials, simplicity and convenience in operation and capability of being suitable for large-scale industrial production.

Enzymatic Baeyer-Villiger oxidation of benzaldehydes

The selectivity of the chemical Baeyer-Villiger oxidation of benzaldehydes depends on steric and electronic factors, the type of oxidizing agent and the reaction conditions. Here we report on the enzymatic Baeyer-Villiger oxidation of fluorobenzaldehydes