53538-03-7Relevant articles and documents
Catalytic activation of carbohydrates as formaldehyde equivalents for stetter reaction with enones
Zhang, Junmin,Xing, Chong,Tiwari, Bhoopendra,Chi, Yonggui Robin
, p. 8113 - 8116 (2013/07/19)
We disclose the first catalytic activation of carbohydrates as formaldehyde equivalents to generate acyl anions as one-carbon nucleophilic units for a Stetter reaction. The activation involves N-heterocyclic carbene (NHC)-catalyzed C-C bond cleavage of carbohydrates via a retro-benzoin-type process to generate the acyl anion intermediates. This Stetter reaction constitutes the first success in generating formal formaldehyde-derived acyl anions as one-carbon nucleophiles for non-self-benzoin processes. The renewable nature of carbohydrates, accessible from biomass, further highlights the practical potential of this fundamentally interesting catalytic activation.
Catalysts for Silylations with 1,1,1,3,3,3-Hexamethyldisilazane
Bruynes, Cornelis A.,Jurriens, Theodorus K.
, p. 3966 - 3969 (2007/10/02)
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