55230-25-6Relevant articles and documents
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Safarov,M.G. et al.
, (1977)
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Catalytic asymmetric [4+2]-cycloaddition of dienes with aldehydes
Liu, Luping,Kim, Hyejin,Xie, Youwei,Fares, Christophe,Kaib, Philip S.J.,Goddard, Richard,List, Benjamin
supporting information, p. 13656 - 13659 (2017/11/06)
Despite its significant potential, a general catalytic asymmetric [4+2]-cycloaddition of simple and electronically unbiased dienes with any type of aldehyde has long been unknown. Previously developed methodologies invariably require activated, electronically engineered substrates. We now provide a general solution to this problem. We show that highly acidic and confined imidodiphosphorimidates (IDPis) are extremely effective Br?nsted acid catalysts of the hetero-Diels-Alder reaction of a wide variety of aldehydes and dienes to give enantiomerically enriched dihydropyrans. Excellent stereoselectivity is generally observed and a variety of scents and natural products can be easily accessed.
CATALYTIC DEHYDRATION OF 4-HEXENE-1,3-DIOL TO 1,3,5-HEXATRIENE
Safarov, M. G.,Bikkulov, R. M.,Safarova, V. G.,Rafikov, S. R.
, p. 789 - 791 (2007/10/02)
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