56472-72-1

Basic information

• Product Name: 1-(4-chlorophenyl)propane-1,2-dione 2-oxime
• CAS NO: 56472-72-1
• Molecular Formula: C₉H₈ClNO₂
• Molecular Weight: 197.6183
• Mol File: 56472-72-1.mol

Chemical Properties

• Boiling Point: 339.2°C at 760 mmHg
• Flash Point: 159°C
• Density: 1.26g/cm³
• Vapor Pressure: 3.62E-05mmHg at 25°C
• Refractive Index: 1.559
• CAS DataBase Reference: 1-(4-chlorophenyl)propane-1,2-dione 2-oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-chlorophenyl)propane-1,2-dione 2-oxime(56472-72-1)
• EPA Substance Registry System: 1-(4-chlorophenyl)propane-1,2-dione 2-oxime(56472-72-1)

Safety Data

• Hazardous Substances Data: 56472-72-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
1-(4-chlorophenyl)propane-1,2-dione 2-oxime is used as an intermediate in the synthesis of various organic compounds due to its unique chemical structure and reactivity.
Used in Pharmaceutical Industry:
1-(4-chlorophenyl)propane-1,2-dione 2-oxime is used as a potential building block for the development of new pharmaceuticals, given its structural features that may offer novel properties and activities.
Used in Material Science:
1-(4-chlorophenyl)propane-1,2-dione 2-oxime may be utilized as a component in the development of new materials, possibly due to its potential to influence the properties of the resulting materials.
(Note: The uses listed are speculative based on the compound's classification and structure. Actual applications may vary and require further investigation and validation through research and experimentation.)

Upstream product

• 6285-05-8 4'-chloropropiophenone 
• 544-16-1 n-Butyl nitrite 
• 123979-03-3 1-(p-Chlorphenyl)-2-methyl-glyoxim 
• 108-90-7 chlorobenzene 

Downstream Products

• 139325-73-8 4-[5-(4-Chloro-phenyl)-4-methyl-3-oxy-imidazol-1-yl]-2-hydroxy-benzoic acid 
• 10557-21-8 1-(4-chlorophenyl)propane-1,2-dione 
• 70071-22-6 2-(4-chlorophenyl)-3-methylquinoxaline 
• 23184-97-6 2-amino-1-(4-chlorophenyl)-1-propanone hydrochloride 
• 78587-05-0 N-cyclohexyl-(4RS,5RS)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide 
• 123979-03-3 1-(4-chlorophenyl)-1,2-propanedione dioxime 

Relevant articles and documents

Dual photoredox/palladium-catalyzed C-H acylation of 2-arylpyridines with oxime esters

An unprecedented dual photoredox/palladium-catalyzed iminyl-radical-mediated C-C bond cleavage and directed ortho C-H acylation of 2-arylpyridines by using oxime esters is described. Oxime esters can serve as efficient acyl sources through formation of the corresponding acyl radicals by photoredox-catalyzed iminyl-radical-mediated C-C bond cleavage. This redox-neutral protocol features excellent regioselectivity, a broad substrate scope, and good functional-group tolerance with respect to both components, giving a broad range of aryl ketones with generally good yields.

Hexythiazox and preparation method thereof

The invention discloses hexythiazox and a preparation method thereof. The method includes: taking chloropropiophenone as a starting material to react with n-butyl nitrite in a mass ratio of 70:47 to generate ketoxime; performing hydrogenation reduction to

An in vivo active 1,2,5-oxadiazole Pt(II) complex: A promising anticancer agent endowed with STAT3 inhibitory properties

New Pt(II) complexes (Pt-1-3) bearing 1,2,5-oxadiazole ligands (1-3) were synthesized, characterized and evaluated for their ability to disrupt STAT3 dimerization. Ligand 3·HCl showed cytotoxic effects on HCT-116 cells (IC50 = 95.2 μM) and a se

A rapid synthesis of quinoxalines starting from ketones

A fast and general synthesis of quinoxalines, performed in two stages or as a one-pot reaction, starting from ketones via their α-hydroxylimino ketone derivatives, and condensation of the latter with 1,2-diaminobenzene under microwave irradiation, is described.

Reaction of Z isomers of alkylaromatic 1,2-hydroxylamino oximes with 1,2-diketones

The reactions of Z isomers of alkylaromatic 1,2-hydroxylamino oximes containing the hydroxylamino group at the primary or secondary carbon atom with diacetyl afford 6-acetyl-5,6-dihydro-4H-1,2,5-oxadiazines. The reactions of these compounds with alkylaromatic 1,2-diketones produce N-substituted α-aroylnitrones or 6-aroyl-5,6-dihydro-4H-1,2,5-oxadiazines or, alternatively, their tautomeric mixtures.

Quinoxalines. Part 13: Synthesis and mass spectrometric study of aryloxymethylquinoxalines and benzo[b]furylquinoxalines

A series of new aryloxymethylquinoxalines, benzo[b]- and naphtho[2,1-b]furylquinoxalines, possessing potential biological activity, was prepared, characterized by IR and NMR spectroscopy and their electron ionization (EI) mass spectra studied in detail. The aryloxymethylquinoxalines were obtained by reacting halogenomethylquinoxalines with bifunctional O-nucleophiles. The benzo[b]furylquinoxalines and naphtho[2,1-b] furylquinoxalines were prepared via two routes, which differed in the order of the two cyclization steps involved in the syntheses. The composition of the ions obtained by EI mass spectrometry were determined by accurate mass measurements and the fragmentation pathways clarified by B/E linked scans and collision induced dissociation. The mass spectrometric behaviour of the compounds studied as to the possible loss of OH· radicals proved to be very characteristic.

A remarkably simple α-oximation of ketones to 1,2-dione monooximes using the chlorotrimethylsilane-isoamyl nitrite combination

Ketones undergo α-oximation by NOCl formed in situ from Me3SiCl and isoamyl nitrite, either in solution or under solvent-free conditions, to produce 1,2-dione monooximes in excellent yields. The oximation is regiospecific in appropriate cases.