5764-85-2

Basic information

• Product Name: ETHYL-3-HYDROXY-3-PHENYL PROPIONATE
• Synonyms: LABDANAX;ETHYL-3-HYDROXY-3-PHENYL PROPIONATE;3-hydroxy-3-phenyl-propionicacidethylester;Benzenepropanoicacid,.beta.-hydroxy-,ethylester;beta-hydroxy-benzenepropanoicaciethylester;beta-hydroxy-benzenepropanoic acid ethyl ester;Ethyl-β-phenyl-β-hydroxypropionate;3-Phenyl-3-hydroxypropanoic acid ethyl ester
• CAS NO: 5764-85-2
• Molecular Formula: C11H14O3
• Molecular Weight: 194.23
• EINECS: 227-288-2
• Mol File: 5764-85-2.mol
• Article Data: 148

Chemical Properties

• Boiling Point: 315.3 °C at 760 mmHg
• Flash Point: 132.6 °C
• Appearance: /Solid
• Density: 1.119
• Vapor Pressure: 0.000186mmHg at 25°C
• Refractive Index: 1.5080
• Storage Temp.: 2-8°C
• PKA: 13.57±0.20(Predicted)
• CAS DataBase Reference: ETHYL-3-HYDROXY-3-PHENYL PROPIONATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL-3-HYDROXY-3-PHENYL PROPIONATE(5764-85-2)
• EPA Substance Registry System: ETHYL-3-HYDROXY-3-PHENYL PROPIONATE(5764-85-2)

Safety Data

• TSCA: Yes
• Hazardous Substances Data: 5764-85-2(Hazardous Substances Data)

Usage

General Description

Ethyl-3-Hydroxy-3-Phenyl Propionate is a chemical compound with the molecular formula C12H14O3. It is commonly used in the fragrance and flavor industry due to its sweet, floral, and fruity aroma. Also known as Ethyl Phenyl Hydroxy Propionate, this compound is often utilized as a key ingredient in perfumes, soaps, and cosmetic products. It is also known for its potential as a flavoring agent in food and beverages. Additionally, Ethyl-3-Hydroxy-3-Phenyl Propionate is researched for its potential biological activities, including its anti-inflammatory and antioxidant properties.

InChI:InChI=1/C11H14O3/c1-2-14-11(13)8-10(12)9-6-4-3-5-7-9/h3-7,10,12H,2,8H2,1H3

Upstream product

• 4071-88-9 trimethylsilanyl-acetic acid ethyl ester 
• 100-52-7 benzaldehyde 
• 60-29-7 diethyl ether 
• 4303-71-3 triphenylmethyl sodium 
• 141-78-6 ethyl acetate 
• 105-36-2 ethyl bromoacetate 
• 93-58-3 benzoic acid methyl ester 
• 42201-84-3 1-ethoxy-1-(tert-butyldimethylsilyloxy)ethene 
• 55134-83-3 5-phenyl-3-ethyl-Δ²-isoxazoline 
• 4192-77-2 ethyl cinnamate 
• 18295-66-4 1-ethoxy-1-(trimethylsiloxy)ethene 
• 103-36-6 ethyl 3-phenyl-2-propenoate 
• 103-82-2 phenylacetic acid 
• 53376-61-7 CH₂=C(OTBS)OEt 

Downstream Products

• 140-10-3 (E)-3-phenylacrylic acid 
• 86217-47-2 3-phenyl-3-hydroxypropionic acid hydrazide 
• 4192-77-2 ethyl cinnamate 
• 3480-87-3 3-hydroxy-3-phenylpropanoic acid 
• 128864-77-7 (S)-3-((R)-2-Fluoro-2-phenyl-acetoxy)-3-phenyl-propionic acid ethyl ester 
• 128864-77-7 (S)-3-((S)-2-Fluoro-2-phenyl-acetoxy)-3-phenyl-propionic acid ethyl ester 
• 127675-72-3 (-)-(S)-Ethyl 3-hydroxy-3-phenylpropanoate Mosher ester 
• 14593-41-0 1,1,3-Triphenyl-1,3-propanediol 
• 103-36-6 ethyl 3-phenyl-2-propenoate 
• 25409-25-0 ethyl 3-acetoxy-3-phenylpropionate 
• 4850-49-1 1-phenyl-1,3-propanediol 
• 2021-28-5 ethyl dihydrocinnamate 
• 70199-99-4 ethyl 3-fluoro-3-phenylpropanoate 
• 7328-39-4 3-sulfydryl-3-phenylpropionic acid 

Relevant articles and documents

Thiourea-catalyzed nucleophilic addition of TMSCN and ketene silyl acetals to nitrones and aldehydes

The effect of hydrogen bonding between nitrones and urea derivatives in the nucleophilic addition reaction was examined. Thioureas bearing an electron-withdrawing group on an aromatic ring, behave like Lewis acid to promote the addition of TMSCN and keten

The Sonochemistry of Zn Powder

-

Photoinduced Oxidative Alkoxycarbonylation of Alkenes with Alkyl Formates

A photoinduced oxidative alkoxycarbonylation of alkenes initiated by intermolecular addition of alkoxycarbonyl radicals has been demonstrated. Employing alkyl formates as alkoxycarbonyl radical sources, a range of α,β-unsaturated esters were obtained with good regioselectivity and E selectivity under ambient conditions.

Synthesis method of beta-hydroxy ester compound

The invention belongs to the technical field of medicine and organic chemical synthesis, and discloses a synthesis method of a beta-hydroxy ester compound. An aldehyde compound and an iodo-acetate compound are used as raw materials; manganese powder is adopted as an accelerant, metal nickel salt is adopted as a catalyst and an organic solvent is adopted as a reaction medium, an organic protonic acid is added and stirred and reacted under inert gas protection, the reaction system is cooled to room temperature after the reaction is finished, vacuum distillation and concentration are performed toobtain a crude product, and column chromatography purification is performed to obtain the beta-hydroxy ester compound. The synthesis method is safe and simple to operate, raw materials are easy to obtain, the price is low, the reaction efficiency is high, and the yield can reach 90% or above and even reach 98%; the method is good in functional group adaptability, wide in substrate adaptability, environmentally friendly, beneficial to industrial production and wide in application in medicine and organic synthesis.