579-44-2Relevant articles and documents
Asymmetric Hydrogenation Cazalyzed by Bis(disubstitiuted glyoximato)cobalt(II)-Chiral Cocatalyst System. Effect of Structural Variation of Ligands and Hydrogen Pressure
Ohgo, Yoshiaki,Tashiro, Yasuhisa,Takeuchi, Seiji
, p. 1549 - 1551 (1987)
The reaction rate was extremely enhanced by increasing the basicity of the axial ligand of and by increasing the hydrogen pressure without decreasing the enantioselectivity.Substituting one and two methyl groups of the dimethylglyoxime liga
Benzaldehyde lyase (BAL)-catalyzed enantioselective CC bond formation in deep-eutectic-solvents-buffer mixtures
Maugeri, Zaira,Dominguez De Maria, Pablo
, p. 120 - 123 (2014)
Deep-eutectic-solvents (DES) have emerged in the last decades as promising bio-based and biodegradable neoteric solvents for biocatalysis, with examples covering different enzymes (mostly hydrolases) and whole-cells (baker's yeast). This paper explores fo
A holoenzyme model of thiamin dependent enzyme; asymmetrical acyloin condensation using a lipid catalyst in a bilayer membrane
Yamashita, Keiji
, p. 4817 - 4820 (1995)
Within a DPPC bilayer membrane, the lipid catalyst 1, having a thiazolium salt unit in the head group, exhibited catalytic activity and enantioselectivity in the acyloin condensation of benzaldehyde. The activity and enantioselectivity were strongly depen
Fungal deracemization of benzoin
Demir, Ayhan S,Hamamci, Haluk,Sesenoglu, Ozge,Neslihanoglu, Rahsan,Asikoglu, Beril,Capanoglu, Doga
, p. 6447 - 6449 (2002)
An enzyme system of Rhizopus oryzae (ATCC 9363) catalyzes the inversion of the chirality of benzoin via a deracemization reaction and, depending on the pH of the medium, both enantiomers of benzoin are obtained in good yield and high ee starting from rac-
SmI2-(Chiral Auxiliary)-Induced Asymmetric Reduction
Takeuchi, Seiji,Ohgo, Yoshiaki
, p. 403 - 404 (1988)
Benzyl was reduced to benzoin with 56.2 percent ee by a system of SmI2-THF-HMPA in the presence of quinidine.
Efficient and Selective Carboligation with Whole-Cell Biocatalysts in Pickering Emulsion
R?llig, Robert,Plikat, Christoph,Ansorge-Schumacher, Marion B.
, p. 12960 - 12963 (2019)
Pickering emulsions (PEs) are particle-stabilized multiphase systems with promising features for synthetic applications. Described here is a novel, simplified set-up employing catalytically active whole cells for simultaneous emulsion stabilization and sy
Purification and covalent immobilization of benzaldehyde lyase with heterofunctional chelate-epoxy modified magnetic nanoparticles and its carboligation reactivity
Tural, Bilsen,Tural, Servet,Ertas, Erdal,Yalinkilic, Ibrahim,Demir, Ayhan S.
, p. 41 - 47 (2013)
In this work, histidine-tagged recombinant benzaldehyde lyase from Pseudomonas fluorescens Biovar I (BAL, EC 4.1.2.38) was immobilized on the magnetically responsive epoxy-chelate magnetic support following a two-step mechanism; that is, the protein is ph
Direct Synthesis of Vinylene Carbonates from Aromatic Aldehydes**
Duguet, Nicolas,Ibrahimli, Leyli,Onida, Killian
supporting information, (2022/04/03)
Substituted vinylene carbonates were directly prepared from aromatic aldehydes following a one-pot Benzoin condensation/transcarbonation sequence under solvent-free conditions. The combination of a N-phenyl substituted triazolium salt NHC precursor and 4-dimethylaminopyridine (DMAP) was found essential to reach high yield and selectivity. The reaction scope was investigated with a range of aromatic aldehydes and the corresponding vinylene carbonates were obtained with 32–86 % isolated yields (14 examples).
Organocatalytic Synthesis of Substituted Vinylene Carbonates
Onida, Killian,Haddleton, Alice J.,Norsic, Sébastien,Boisson, Christophe,D'Agosto, Franck,Duguet, Nicolas
supporting information, p. 5129 - 5137 (2021/09/18)
The organocatalytic synthesis of substituted vinylene carbonates from benzoins and acyloins was studied using diphenyl carbonate as a carbonyl source. A range of N-Heterocyclic Carbene (NHC) precursors were screened and it was found that imidazolium salts were the most active for this transformation. The reaction occurs at 90 °C under solvent-free conditions. A wide range of substituted vinylene carbonates (symmetrical and unsymmetrical, aromatic or aliphatic), including some derived from natural products, were prepared with 20–99% isolated yields (24 examples). The reaction was also developed using thermomorphic polyethylene-supported organocatalysts as recoverable and recyclable species. The use of such species facilitates the workup and allows the synthesis of vinylene carbonates on the preparative scale (>30 g after 5 runs). (Figure presented.).