41728-16-9

Basic information

• Product Name: 1,2-diphenylpropane-1,2-diol
• CAS NO: 41728-16-9
• Molecular Formula: C₁₅H₁₆O₂
• Molecular Weight: 228.2863
• Mol File: 41728-16-9.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 382.9°C at 760 mmHg
• Flash Point: 182.2°C
• Density: 1.164g/cm³
• Vapor Pressure: 1.52E-06mmHg at 25°C
• Refractive Index: 1.605
• CAS DataBase Reference: 1,2-diphenylpropane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-diphenylpropane-1,2-diol(41728-16-9)
• EPA Substance Registry System: 1,2-diphenylpropane-1,2-diol(41728-16-9)

Safety Data

• Hazardous Substances Data: 41728-16-9(Hazardous Substances Data)

Usage

Appearance

White, crystalline solid

Odor

Slightly sweet

Uses

a. Precursor in the synthesis of dyes, pharmaceuticals, and perfumes
b. Intermediate in the production of plasticizers and UV absorbers

Properties

a. Antibacterial
b. Antifungal

Applications

a. Medical and personal care products
b. Industrial and commercial uses
c. Synthesis of various products

Upstream product

• 123-91-1 1,4-dioxane 
• 2999-74-8 dimethylmagnesium 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 90-63-1 (RS)-1-hydroxy-1-phenylpropan-2-one 
• 98-86-2 acetophenone 
• 100-51-6 benzyl alcohol 
• 451-40-1 phenyl benzyl ketone 
• 917-64-6 methyl magnesium iodide 
• 917-54-4 methyllithium 
• 201230-82-2 carbon monoxide 
• 100-52-7 benzaldehyde 
• 23022-83-5 1-bromo-1-phenyl-2-propanone 
• 779-51-1 cis-α-methylstilbene 
• 833-81-8 1,2-diphenylpropene 

Downstream Products

• 22875-82-7 2,2-diphenylpropanal 
• 13733-16-9 erythro-1,2-Dihydroxy-1,2-diphenyl-propan-1-acetat 
• 4505-48-0 2-phenylindene 
• 4915-86-0 2-acetoxy-1,2-diphenyl-propan-1-one 
• 2042-85-5 1,2-diphenylpropan-1-one 
• 67700-01-0 4-bromo-benzenesulfonic acid-((1RS,2RS)-1,2-diphenyl-propyl ester) 
• 7693-84-7 (1RS,2RS)-1,2-diphenyl-propan-1-ol 
• 4829-02-1 2-hydroxy-2-phenylcyclohexanone 
• 87258-30-8 6-oxo-6-phenylhexanal 
• 5623-26-7 α-methylbenzoin 
• 64-19-7 acetic acid 
• 98-86-2 acetophenone 
• 65-85-0 benzoic acid 

Relevant articles and documents

Catalytic Reductive Cross-Coupling between Aromatic Aldehydes and Arylnitriles

A reductive cross-coupling reaction between aromatic aldehydes and arylnitriles using a copper catalyst and a silylboronate as a reductant is reported. This protocol represents an unprecedented approach to the chemoselective synthesis of α-hydroxy ketones by electrophile–electrophile cross-coupling.

Novel biphenyl organocatalysts for iminium ion-catalyzed asymmetric epoxidation

Two novel chiral biphenyl iminium salts derived from L-acetonamine, containing electron-withdrawing 3,30-substituents on the biphenyl unit, have been prepared and tested as asymmetric catalysts for epoxidation of prochiral alkenes. The results are compared with those achieved using the corresponding unsubstituted system.

Lanthanum tricyanide-catalyzed acyl silane-ketone benzoin additions and kinetic resolution of resultant α-silyloxyketones

We report the full account of our efforts on the lanthanum tricyanide-catalyzed acyl silane-ketone benzoin reaction. The reaction exhibits a wide scope in both acyl silane (aryl, alkyl) and ketone (aryl-alkyl, alkyl-alkyl, aryl-aryl, alkenyl-alkyl, alkynyl-alkyl) coupling partners. The diastereoselectivity of the reaction has been examined in both cyclic and acyclic systems. Cyclohexanones give products arising from equatorial attack by the acyl silane. The diastereoselectivity of acyl silane addition to acyclic α-hydroxy ketones can be controlled by varying the protecting group to obtain either Felkin-Ahn or chelation control. The resultant α-silyloxyketone products can be resolved with selectivity factors from 10 to 15 by subjecting racemic ketone benzoin products to CBS reduction.