61425-27-2

Basic information

• Product Name: N-BENZYLOXYCARBONYL-D-ALANINOL
• Synonyms: N-BENZYLOXYCARBONYL-D-ALANINOL;N-CBZ-D-ALANINOL;N-Z-D-ALANINOL;(R)-(+)-2-(Z-AMINO)-1-PROPANOL;Z-D-ALANINOL;CBZ-D-ALANINOL;(R)-2-CBZ-AMINOPROPANOL;Z-D-Ala-ol
• CAS NO: 61425-27-2
• Molecular Formula: C₁₁H₁₅NO₃
• Molecular Weight: 209.24
• EINECS: 1533716-785-6
• Product Categories: PROTECTED AMINO ACID & PEPTIDES;Amino Acid Derivatives;Amino Alcohols;Peptide Synthesis
• Mol File: 61425-27-2.mol

Chemical Properties

• Melting Point: 82-84°C
• Boiling Point: 375.2 °C at 760 mmHg
• Flash Point: 180.7 °C
• Appearance: /
• Density: 1.149g/cm³
• Vapor Pressure: 2.7E-06mmHg at 25°C
• Refractive Index: 1.534
• Storage Temp.: 2-8°C
• PKA: 11.90±0.46(Predicted)
• CAS DataBase Reference: N-BENZYLOXYCARBONYL-D-ALANINOL(CAS DataBase Reference)
• NIST Chemistry Reference: N-BENZYLOXYCARBONYL-D-ALANINOL(61425-27-2)
• EPA Substance Registry System: N-BENZYLOXYCARBONYL-D-ALANINOL(61425-27-2)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 61425-27-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
N-Benzyloxycarbonyl-D-alaninol is used as a key intermediate in the synthesis of pharmaceuticals for its ability to protect the amine group during the synthesis process. This protection allows for the selective formation of desired peptide bonds and the creation of complex molecular structures with enhanced stability and bioavailability.
Used in Peptide Synthesis:
In peptide synthesis, N-Benzyloxycarbonyl-D-alaninol is used as a building block to construct peptide sequences. The Z group on the compound facilitates the stepwise assembly of peptides by preventing unwanted side reactions, thus improving the yield and purity of the final peptide product.
Used in Bioactive Compound Production:
N-Benzyloxycarbonyl-D-alaninol is employed as a precursor in the production of bioactive compounds, such as antibiotics, enzymes, and other therapeutic agents. Its role in protecting the amine group during synthesis contributes to the development of more effective and targeted biologically active molecules.
Used in Chemical Research:
In the field of chemical research, N-Benzyloxycarbonyl-D-alaninol is utilized as a reagent and a model compound for studying the properties and reactions of amino acids and their derivatives. Its unique structure and functional groups make it an invaluable tool for understanding the fundamental principles of organic and biochemistry.

InChI:InChI=1/C11H15NO3/c1-9(7-13)12-11(14)15-8-10-5-3-2-4-6-10/h2-6,9,13H,7-8H2,1H3,(H,12,14)/t9-/m1/s1

Upstream product

• 6168-72-5 2-Amino-1-propanol 
• 501-53-1 benzyl chloroformate 
• 124-68-5 2-Amino-2-methyl-1-propanol 
• 2749-11-3 (S)-Alaninol 
• 4132-86-9 N-benzyloxycarbonylalanine 
• 105499-10-3 (1(S)-methyl-2-oxo-ethyl)-carbamic acid benzyl ester 
• 28819-05-8 (S)-2-benzyloxycarbonylamino-propionic acid methyl ester 
• 1142-20-7 N-Cbz-Ala 
• 65638-93-9 N-Carbobenzoxy-L-alanin-kohlensaeureaethylesteranhydrid 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 56-41-7 L-alanin 
• 25172-67-2 Z-Ala-O-COO-isoBu 
• 3401-36-3 (N-benzyloxycarbonyl)-L-alanine N-hydroxysuccinimide ester 
• 99790-15-5 ((S)-2-Imidazol-1-yl-1-methyl-2-oxo-ethyl)-carbamic acid benzyl ester 

Downstream Products

• 145799-47-9 (R)-(+)-benzyl 2-(benzyloxycarbonylamino)propyl carbonate 
• 145799-47-9 (S)-(-)-benzyl 2-(benzyloxycarbonylamino)propyl carbonate 
• 145799-44-6 (R)-(+)-2-(benzyloxycarbonylamino)propyl acetate 
• 124460-18-0 (S)-(-)-2-(benzyloxycarbonylamino)propyl acetate 
• 667452-19-9 2-(benzyloxycarbonylamino)propyl methanesulfonate 
• 105499-10-3 (1(S)-methyl-2-oxo-ethyl)-carbamic acid benzyl ester 
• 1440418-59-6 (S)-di-tert-butyl 1-(2-(((benzyloxy)carbonyl)amino)-1-oxopropan-2-yl)hydrazine-1,2-dicarboxylate 
• 142056-17-5 Z-ALa-Ψ(CH2)Gly-OCH3 
• 138588-01-9 O-(2-O-acetyl-3,4-di-O-methyl-α-L-rhamnopyranosyl)-N-carbobenzyloxy-L-alanilol 
• 1142-20-7 N-Cbz-Ala 
• 82353-55-7 benzyl (S)-1-oxopropan-2-ylcarbamate 
• 124460-19-1 1-tert-butyldimethylsilyloxy-(2S)-N-benzyloxycarbonylaminopropane 
• 83197-70-0 (S)-2-(benzyloxycarbonylamino)propyl methanesulfonate 
• 946088-68-2 benzyl 2-methylaziridine-1-carboxylate 

Relevant articles and documents

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