65638-93-9

Basic information

• Product Name: N-Carbobenzoxy-L-alanin-kohlensaeureaethylesteranhydrid
• Synonyms: N-Carbobenzoxy-L-alanin-kohlensaeureaethylesteranhydrid
• CAS NO: 65638-93-9
• Molecular Weight: 295.292
• Mol File: 65638-93-9.mol
• Article Data: 26

Chemical Properties

• CAS DataBase Reference: N-Carbobenzoxy-L-alanin-kohlensaeureaethylesteranhydrid(CAS DataBase Reference)
• NIST Chemistry Reference: N-Carbobenzoxy-L-alanin-kohlensaeureaethylesteranhydrid(65638-93-9)
• EPA Substance Registry System: N-Carbobenzoxy-L-alanin-kohlensaeureaethylesteranhydrid(65638-93-9)

Safety Data

• Hazardous Substances Data: 65638-93-9(Hazardous Substances Data)

Upstream product

• 1142-20-7 N-Cbz-Ala 
• 541-41-3 chloroformic acid ethyl ester 
• 16357-59-8 N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 1456813-86-7 C₁₉H₂₂N₂O₄ 
• 145118-42-9 N²-(benzyloxycarbonyl)-N¹-<2-(1H-indol-3-yl)ethyl>alaninamid 
• 2483-51-4 N-[(benzyloxy)carbonyl]-L-alanyl-L-alanine methyl ester 
• 4840-29-3 Z-L-Ala-Gly-OMe 
• 13122-97-9 N-benzyloxycarbonyl-L-alanyl-L-tyrosine 
• 122400-20-8 [(benzyloxy)carbonyl]-L-alanyl-L-cysteine 
• 17460-58-1 (2S)-2-[((2S)-2-{[(benzyloxy)carbonyl]amino}propanoyl)amino]-3-hydroxypropanoic acid 
• 17343-54-3 (S)-2-(benzyloxycarbonylamino)-propionitrile 
• 136464-11-4 (S)-2-benzyloxycarbonylamino-1-iodopropane 
• 190393-64-7 (S)-2-[(benzyloxycarbonyl)amino]propan-1-yl azide 
• 1638689-56-1 C₂₁H₂₉N₅O₅ 
• 1638689-27-6 C₁₄H₁₆N₄O₄ 
• 114744-83-1 (S)-benzyl (1-(N,O-dimethylhydroxylamine)-1-oxopropan-2-yl)carbamate 
• 98642-72-9 C₁₈H₂₀N₂O₃ 

Relevant articles and documents

Facile synthesis of optically active imidazole derivatives

Five optically active imidazole derivatives have been synthesized via a facile 4-step reaction sequence starting from commercially available and inexpensive N-Cbz amino acids. While microwave assisted condensation was unsuccessful, the condensation of the

Synthesis of Acetaminophen Analogues Containing α-Amino Acids and Fatty Acids for Inhibiting Hepatotoxicity

Acetaminophen is a popular antipyretic analgesic medicine that has weaker anti-inflammatory properties and lower incidence of side effects than nonsteroidal anti-inflammatory drugs (NSAIDs). However, acetaminophen causes hepatotoxicity due to the reactive metabolite N -acetyl- p -benzoquinone imine (NAPQI). We have obtained acetaminophen analogues in 57-99percent yields by using aniline derivatives with protected α-amino acids and fatty acids via the corresponding mixed carbonic carboxylic anhydrides in aqueous MeCN. We have also succeeded in synthesizing AM404 analogues in 76-97percent yields, which are expected to be promising candidates for reducing hepatotoxicity.

Double axial chirality promoted asymmetric [2,3] Stevens rearrangement of N-cinnamyl l-alanine amide-derived ammonium ylides

The base-induced asymmetric [2,3] Stevens rearrangement of N-cinnamyl tetraalkylammonium ylides derived from l-alanine amides proceeds via a double axially chiral intermediate to afford the corresponding α-substituted alanine derivatives with high enantio- and diastereoselectivities. the Partner Organisations 2014.