71255-03-3Relevant articles and documents
Total Synthesis of Frustulosin and Aurocitrin
Ronald, Robert C.,Lansinger, Janet M.,Lillie, Thomas S.,Wheeler, Carl J.
, p. 2541 - 2549 (2007/10/02)
The regioselective total syntheses of the novel fungal antibiotics frustulosin (1) and aurocitrin (2) were accomplished from 3,6-dihydroxy-2-iodobenzaldehyde (10) which was prepared by a regiodirected metalation of 2,5-dimethylbenzyl vinyl ether to establish the 1,2,3,4-tetrasubstitution pattern of these compounds.The unsaturated side chains of these hydroquinone antibiotics were attached by using the iodo aldehyde functionalities.The structures of these antibiotics are confirmed by synthesis.