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73549-09-4

(Z)-2-ACETAMIDO-3-(4-METHOXYPHENYL)ACRYLIC ACID is a chemical compound with the molecular formula C12H13NO4. It is an acrylamide derivative that contains an amide functional group. This white solid at room temperature is sparingly soluble in water and is known for its potential biological activity. Its chemical structure and properties make it a subject of interest for further study and potential applications in the pharmaceutical industry.

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  • 73549-09-4 Structure

  • Basic information

    1. Product Name: (Z)-2-ACETAMIDO-3-(4-METHOXYPHENYL)ACRYLIC ACID
    2. Synonyms: (Z)-2-ACETAMIDO-3-(4-METHOXYPHENYL)ACRYLIC ACID
    3. CAS NO:73549-09-4
    4. Molecular Formula: C12H13NO4
    5. Molecular Weight: 235.23592
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 73549-09-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: (Z)-2-ACETAMIDO-3-(4-METHOXYPHENYL)ACRYLIC ACID(CAS DataBase Reference)
    10. NIST Chemistry Reference: (Z)-2-ACETAMIDO-3-(4-METHOXYPHENYL)ACRYLIC ACID(73549-09-4)
    11. EPA Substance Registry System: (Z)-2-ACETAMIDO-3-(4-METHOXYPHENYL)ACRYLIC ACID(73549-09-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 73549-09-4(Hazardous Substances Data)

73549-09-4 Usage

Uses

Used in Pharmaceutical Research:
(Z)-2-ACETAMIDO-3-(4-METHOXYPHENYL)ACRYLIC ACID is used as a research compound for its potential biological activity. Its unique structure and properties make it a promising candidate for the development of new pharmaceuticals.
Used in Organic Synthesis:
In the field of organic synthesis, (Z)-2-ACETAMIDO-3-(4-METHOXYPHENYL)ACRYLIC ACID is used as a key intermediate for the synthesis of various organic compounds.
Used in Drug Development:
Due to its anti-inflammatory and analgesic properties, (Z)-2-ACETAMIDO-3-(4-METHOXYPHENYL)ACRYLIC ACID is used as a potential candidate for drug development, particularly for the treatment of pain and inflammation.
Used in the Pharmaceutical Industry:
(Z)-2-ACETAMIDO-3-(4-METHOXYPHENYL)ACRYLIC ACID is used in the pharmaceutical industry for its potential applications in the development of new drugs and therapies. Its unique chemical structure and properties make it a valuable asset for research and development efforts.

Check Digit Verification of cas no

The CAS Registry Mumber 73549-09-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,5,4 and 9 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 73549-09:
(7*7)+(6*3)+(5*5)+(4*4)+(3*9)+(2*0)+(1*9)=144
144 % 10 = 4
So 73549-09-4 is a valid CAS Registry Number.

73549-09-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name (Z)-2-acetamido-3-(4-methoxyphenyl)-2-propenoic acid

1.2 Other means of identification

Product number -
Other names (Z)-2-ACETAMIDO-3-(4-METHOXYPHENYL)ACRYLIC ACID

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:73549-09-4 SDS

73549-09-4Relevant articles and documents

Synthesis of new simplified hemiasterlin derivatives with α,β-unsaturated carbonyl moiety

The, Chinh Pham,Thi, Tuyet Anh Dang,Hoang, Thi Phuong,Ngo, Quoc Anh,Doan, Duy Tien,Thi, Thu Ha Nguyen,Thi, Tham Pham,Thi, Thu Ha Vu,Jean,Van De Weghe,Van, Tuyen Nguyen

supporting information, p. 2244 - 2246 (2014/05/20)

In this Letter, we report a convenient and efficient method for the synthesis of new simplified derivatives of hemiasterlin in which the α,α-dimethylbenzylic moiety A is replaced by α,β- unsaturated aryl groups as Michael acceptor. Most of these derivatives have a strong cytotoxic activity on three human tumor cell lines (KB, Hep-G2 and MCF7). Analogs 17b and 17f showed a high cytotoxicity against KB and Hep-G2 cancer cell lines comparable to paclitaxel and ellipticine.

Synthesis of oxazoles from enamides via phenyliodine diacetate-mediated intramolecular oxidative cyclization

Zheng, Yunhui,Li, Xuming,Ren, Chengfeng,Zhang-Negrerie, Daisy,Du, Yunfei,Zhao, Kang

, p. 10353 - 10361 (2013/01/15)

A group of functionalized oxazoles were synthesized in moderate to good yields from enamides via phenyliodine diacetate (PIDA)-mediated intramolecular cyclization. The main advantageous features of the present method include its broad substrate scope and the heavy-metal-free characteristic of the oxidative carbon-oxygen bond formation process.

SYNTHESIS OF DEHYDROPHENYLALANINE DERIVATIVES BY PALLADIUM CATALYZED ARYLATION OF 2-ACETAMIDOACRYLIC ACID

Cutolo, M.,Fiandanese, V.,Naso, F.,Sciacovelli, O.

, p. 4603 - 4606 (2007/10/02)

Arylation of 2-acetamidoacrylic acid using Pd(OAc)2/PPh3 or PdCl2(PPh3)2 as catalytic systems leads to α-acetamidocinnamic acids of Z configuration.

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