132165-61-8

Basic information

• Product Name: 2-Propenoic acid, 2-(acetylamino)-3-(4-methoxyphenyl)-, methyl ester
• CAS NO: 132165-61-8
• Molecular Formula: C13H15NO4
• Molecular Weight: 249.266
• Mol File: 132165-61-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 2-(acetylamino)-3-(4-methoxyphenyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 2-(acetylamino)-3-(4-methoxyphenyl)-, methyl ester(132165-61-8)
• EPA Substance Registry System: 2-Propenoic acid, 2-(acetylamino)-3-(4-methoxyphenyl)-, methyl ester(132165-61-8)

Safety Data

• Hazardous Substances Data: 132165-61-8(Hazardous Substances Data)

Upstream product

• 104-92-7 1-bromo-4-methoxy-benzene 
• 35356-70-8 Methyl 2-acetamidoacrylate 
• 123-11-5 4-methoxy-benzaldehyde 
• 67-56-1 methanol 
• 73549-09-4 (Z)-2-acetamido-3-(4-methoxyphenyl)-2-propenoic acid 
• 71198-72-6 4-[(4-methoxyphenyl)methylene]-2-methyl-5(4H)-oxazolone 
• 124-41-4 sodium methylate 
• 543-24-8 N-acetylglycine 
• 71198-72-6 (4Z)-4-(4-methoxybenzylidene)-2-methyl-oxazolin-5-one 
• 66107-29-7 4-methoxyphenyl triflate 

Downstream Products

• 32058-04-1 4-(4-methoxy-phenyl)-1⁽²⁾H-pyrazole-3-carboxylic acid methyl ester 
• 111016-45-6 4-(4-methoxyphenyl)-1H-pyrazole 
• 110356-26-8 4-(4-methoxyphenyl)-1H-pyrazole-3-carboxylic acid 
• 17355-24-7 (S)-N-acetyl-3-(4-methoxyphenyl)alanine methyl ester 
• 17355-24-7 methyl (R)-2-acetamido-3-(4-methoxyphenyl)propanoate 
• 131305-24-3 (Z)-2-(Acetyl-methyl-amino)-3-(4-methoxy-phenyl)-acrylic acid methyl ester 
• 105962-45-6 cis-4-p-methoxyphenyl-3-acetamido-3-carbomethoxy-Δ¹-pyrazoline 
• 70529-50-9 methyl 2-acetylamino-3-(4-methoxyphenyl)propanoate 
• 105962-33-2 (Z)-2-acetylamino-3-(4-methoxyphenyl)but-2-enoic acid methyl ester 

Relevant articles and documents

Silver-Promoted Direct Phosphorylation of Bulky C(sp2)-H Bond to Build Fully Substituted β-Phosphonodehydroamino Acids

A general and practical cross-dehydrogenative coupling protocol between readily available trisubstituted α,β-dehydro α-amino carboxylic esters and H-phosphites is described. This C(sp2)-H phosphorylation reaction proceeds with absolute Z-selectivity promoted by silver salt in a radical relay manner. The bulky tetrasubstituted β-phosphonodehydroamino acids were obtained in grams and added new modules to the toolkit for peptide modifications.

An Atropos Chiral Biphenyl Bisphosphine Ligand Bearing Only 2,2′-Substituents and Its Application in Rh-Catalyzed Asymmetric Hydrogenation

An atropos chiral biphenyl bisphosphine ligand bearing only 2,2′-substituents was rationally designed and easily synthesized utilizing a bulky chiral t-butylmethylphosphino block. Computational results showed a large difference in the free energies betwee

Cation-triggered switchable asymmetric catalysis with chiral aza-crownphos

An aza-crown ether, modified phosphoramidite ligand, has been designed and synthesized. The ON/OFF reversible switch of catalytic activity for its rhodium catalyst was thoroughly investigated in the asymmetric hydrogenation of dehydroamino acid esters modulated by host-guest interactions. In the OFF state, the catalyst is almost inactive (less than 1% conversion) because of the formation of an intermolecular sandwich complex by two aza-crown ether moities and the cationic rhodium metal center. In using alkali-metal-cations as the trigger, the catalytic activity was turned ON and consequently resulted in full conversions and excellent enantioselectivities (up to 98% ee).