74037-50-6

Basic information

• Product Name: 3-ETHOXY-2-NITROPYRIDINE
• Synonyms: 3-ETHOXY-2-NITROPYRIDINE;2-NITRO-3-ETHOXY PYRIDINE;3-ethoxy-2-nitro-pyridin;3-Ethoxy-2-nitropyridine,98%
• CAS NO: 74037-50-6
• Molecular Formula: C₇H₈N₂O₃
• Molecular Weight: 168.15
• EINECS: 277-676-0
• Product Categories: Pyridines, Pyrimidines, Purines and Pteredines;Pyridines;Pyridine
• Mol File: 74037-50-6.mol

Chemical Properties

• Melting Point: 28-32 °C
• Boiling Point: 175-175 °C (50 mmHg)
• Flash Point: 38 °C
• Appearance: light yellow crystals or crystalline solid
• Density: 1.3722 (rough estimate)
• Vapor Pressure: 0.0092mmHg at 25°C
• Refractive Index: 1.5200 (estimate)
• Storage Temp.: Flammables area
• BRN: 141592
• CAS DataBase Reference: 3-ETHOXY-2-NITROPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ETHOXY-2-NITROPYRIDINE(74037-50-6)
• EPA Substance Registry System: 3-ETHOXY-2-NITROPYRIDINE(74037-50-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-10
• Safety Statements: 24/25-16-36/37/39-26
• RIDADR: 1993
• RTECS: UT3001500
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 74037-50-6(Hazardous Substances Data)

Usage

Chemical Properties

light yellow crystals or crystalline solid

InChI:InChI=1/C7H8N2O3/c1-2-12-6-4-3-5-8-7(6)9(10)11/h3-5H,2H2,1H3

Upstream product

• 14773-50-3 3-ethoxypyridine 
• 626-55-1 3-Bromopyridine 
• 15128-82-2 3-hydroxy-2-nitropyridine 
• 75-03-6 ethyl iodide 
• 54231-35-5 3-fuoro-2-nitropyridine 
• 64-17-5 ethanol 

Downstream Products

• 6602-32-0 2-bromo-pyridin-3-ol 
• 10006-74-3 2-Amino-3-(ethoxy)pyridine 
• 13269-19-7 3-amino-2-nitropyridine 
• 89694-54-2 2-bromo-3-ethoxypyridine 
• 847225-55-2 3-ethoxy-2-fluoropyridine 
• 15128-82-2 3-hydroxy-2-nitropyridine 
• 847225-57-4 2-nitro-3-(3-aminobenzyloxy)pyridine 
• 847225-59-6 2-nitro-3-(3-t-butoxycarbonylaminobenzyloxy)pyridine 
• 89943-11-3 2-amino-5-ethoxypyridine 
• 137347-01-4 3-ethoxy-2-bromo-6-nitro-pyridine 
• 16867-03-1 2-amino-3-hydroxypyridine 

Relevant articles and documents

NOVEL COMPOUNDS FOR MODULATION OF ROR-GAMMA ACTIVITY

The present invention relates to aryl sulfones and related compounds that are modulators of ROR-gamma receptors. The invention also provides pharmaceutical compositions comprising these modulators, and methods of modulating ROR-gamma receptors using them. Also provided are methods of using aryl sulfones and related compounds as modulators of ROR-gamma to treat ROR-gamma mediated diseases

BIARYL-CONTAINING COMPOUNDS AS INVERSE AGONISTS OF ROR-GAMMA RECEPTORS

The present invention relates to biaryl-containing inverse agonists of ROR-gamma receptors. The invention also provides pharmaceutical compositions comprising these biaryl- containing inverse agonists, and methods of modulating ROR-gamma receptors using these inverse agonists. Also provided are methods of using biaryl-containing inverse agonists to treat ROR-gamma mediated diseases.

BIPYRIDYL AMINES AND ETHERS AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR-5

The present invention is directed to novel bipyridyl amine and ether compounds such as those of Formula (I): (I) (where R?1#191, R?2#191, R?3#191, X and Y are as defined herein) which are mGluR5 modulators useful in the treatment or prevention of diseases and conditions in which mGluR5 is involved, including but not limited to psychiatric and mood disorders such as schizophrenia, anxiety, depression, bipolar disorders, and panic, as well as in the treatment of pain, Parkinson’s disease, cognitive dysfunction, epilepsy, circadian rhythm and sleep disorders, such as shift-work induced sleep disorder and jet-lag, drug addiction, drug abuse, drug withdrawal, obesity and other diseases. The invention is also directed to pharmaceutical compositions comprising these compounds. This invention further provides a method of treatment of these disorders and conditions by the administration of an effective amount of these novel bipyridyl amine and/or ether compounds and/or compositions containing these compounds.