829-20-9

Basic information

• Product Name: 2,4-Dimethoxyacetophenone
• Synonyms: 2',4'-DIMETHOXYACETOPHENONE;2,4-DIMETHOXYACETOPHENONE;AKOS BBS-00004235;1-(2,4-Dimethoxy-phenyl)-ethanone;Acetophenone, 2',4'-dimethoxy-;Ethanone, 1-(2,4-dimethoxyphenyl)-;2',4'-Dimethoxyacethophenone, 98%;1-Acetyl-2,4-dimethoxybenzene
• CAS NO: 829-20-9
• Molecular Formula: C₁₀H₁₂O₃
• Molecular Weight: 180.2
• EINECS: 212-587-2
• Product Categories: Aromatic Acetophenones & Derivatives (substituted);Acetophenone series;Building Blocks;C10;Carbonyl Compounds;Chemical Synthesis;Ketones;Organic Building Blocks
• Mol File: 829-20-9.mol
• Article Data: 62

Chemical Properties

• Melting Point: 37-40 °C(lit.)
• Boiling Point: 288 °C(lit.)
• Flash Point: >230 °F
• Appearance: White to off-white/Crystalline Powder
• Density: 1.1272 (rough estimate)
• Refractive Index: 1.5430 (estimate)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Sensitive: Light Sensitive
• BRN: 511947
• CAS DataBase Reference: 2,4-Dimethoxyacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Dimethoxyacetophenone(829-20-9)
• EPA Substance Registry System: 2,4-Dimethoxyacetophenone(829-20-9)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 24/25
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 829-20-9(Hazardous Substances Data)

Usage

Chemical Properties

white to off-white crystalline powder

Preparation

Obtained by reaction of dimethyl sulfate with resacetophenone in the presence of 10% aqueous sodium hydroxide (61%).

InChI:InChI=1/C10H12O3/c1-7(11)9-5-4-8(12-2)6-10(9)13-3/h4-6H,1-3H3

Upstream product

• 108-24-7 acetic anhydride 
• 151-10-0 1,3-Dimethoxybenzene 
• 64-19-7 acetic acid 
• 75-36-5 acetyl chloride 
• 552-41-0 1-(2-hydroxy-4-methoxyphenyl)ethanone 
• 74-88-4 methyl iodide 
• 75-05-8 acetonitrile 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 
• 18986-10-2 2',4'-Dihydroxyacetophenondimethylhydrazon 
• 77-78-1 dimethyl sulfate 
• 7446-70-0 aluminium trichloride 
• 91143-38-3 1-(4-acetoxy-2-methoxy-phenyl)-ethanone 
• 98-95-3 nitrobenzene 
• 616-38-6 carbonic acid dimethyl ester 

Downstream Products

• 18493-28-2 2',4'-dimethoxy-4-nitro-chalcone 
• 1154-77-4 2',4'-dimethoxychalcone 
• 23423-35-0 (E)‐3‐(4‐hydroxyphenyl)‐1‐(2,4‐dimethoxyphenyl)prop‐2‐en‐1‐one 
• 18493-30-6 1-(2,4-dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one 
• 30925-62-3 metochalcone 
• 13330-65-9 2,4-dimethoxyphenol 
• 93878-60-5 (2E)-1-(2,4-dimethoxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-one 
• 66346-54-1 1-(2,4-dimethoxy-phenyl)-hexane-1,3-dione 
• 7760-63-6 ethyl 3-(2',4'-dimethoxyphenyl)but-2-enoate 
• 7706-67-4 3-(2,4-dimethoxy-phenyl)-cis-crotonic acid 
• 21523-72-8 1-(2,4-dimethoxy-phenyl)-2-methyl-3-morpholin-4-yl-propan-1-one 
• 18703-83-8 1-(2,4-dimethoxy-phenyl)-3-morpholin-4-yl-propan-1-one 
• 35045-66-0 4-(2,4-dimethoxy-phenyl)-2-morpholin-4-yl-4-oxo-butyric acid 
• 13751-92-3 2-(2,4-Dimethoxy-phenyl)-3-methyl-octen-⁽²⁾ 

Relevant articles and documents

Peptoid Helix Displaying Flavone and Porphyrin: Synthesis and Intramolecular Energy Transfer

Natural light-harvesting complexes (LHCs) absorb a broad spectrum of sunlight using a collection of photosynthetic pigments whose spatial arrangement is controlled by a protein matrix and exhibit efficient energy transfer. We constructed a novel light-harvesting protein mimic, which absorbs light in the UV to visible region (280-700 nm) by displaying flavone and porphyrin on a peptoid helix. First, an efficient synthesis of 4′-derivatized 7-methoxyflavone (7-MF, 3 and 4) was developed. The flavone-porphyrin-peptoid conjugate (FPPC) was then prepared via Miyaura borylation on a resin-bound peptoid followed by Suzuki coupling between the peptoid and pigment. Circular dichroism spectroscopy indicated that the FPPC underwent helix-to-loop conversion of the peptoid scaffold upon changing the solvent conditions. A distinct intramolecular energy transfer was observed from 7-MF to porphyrin with greater efficiency in the helix than that in the loop conformation of the peptoid, whereas no clear evidence of energy transfer was obtained for unstructured FPPC. We thus demonstrate the value of the helical peptoid, which provided a controlled orientation for 7-MF and porphyrin and modulated the energy transfer efficiency via conformational switching. Our work provides a way to construct a sophisticated LHC mimic with enhanced coverage of the solar spectrum and controllable energy transfer efficiency.

Dihydropyrazole MurA enzyme inhibitor molecule as well as preparation method and application thereof

The invention provides a dihydropyrazole MurA enzyme inhibitor molecule as well as a preparation method and application thereof. The structural formula is shown in the specification, R is a direct-connected alkyl group with the chemical formula of CnH2n+1, and n is equal to 1-7. The preparation method comprises the following steps of by taking acetophenone substances with different substituent groups and 4-(4-methyl piperazinyl) benzaldehyde as raw materials, carrying out aldol condensation reaction under an alkaline condition to obtain an intermediate, and synthesizing a target compound with a structural formula by using the intermediate, hydrazine hydrate and an organic acid with an R-COOH structure. The dihydropyrazole MurA enzyme inhibitor molecule provided by the invention has a bacterial inhibition effect, has an MurA enzyme inhibition effect, and also has an effect of interfering synthesis of bacterial cell walls.

Imidazolium Triflate Ionic Liquid Improves the Activity of ZnCl2 in the Synthesis of Pyrroles and Ketones

-