83247-00-1

Basic information

• Product Name: 2-bromo-6-phenoxypyridine
• Synonyms: 2-bromo-6-phenoxypyridine
• CAS NO: 83247-00-1
• Molecular Formula: C₁₁H₈BrNO
• Molecular Weight: 250.09132
• Mol File: 83247-00-1.mol

Chemical Properties

• Melting Point: 83-86 °C
• Boiling Point: 327.2±27.0 °C(Predicted)
• Appearance: /
• Density: 1.476±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: -1.90±0.12(Predicted)
• CAS DataBase Reference: 2-bromo-6-phenoxypyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-6-phenoxypyridine(83247-00-1)
• EPA Substance Registry System: 2-bromo-6-phenoxypyridine(83247-00-1)

Safety Data

• Hazardous Substances Data: 83247-00-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2-bromo-6-phenoxypyridine is used as a building block for the synthesis of various heterocyclic compounds, contributing to the development of new organic molecules with unique properties and potential applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-bromo-6-phenoxypyridine is used as an intermediate in the development of new drugs, leveraging its chemical structure to create novel therapeutic agents with improved efficacy and selectivity.
Used in Agrochemical Industry:
2-bromo-6-phenoxypyridine is utilized as a key component in the synthesis of pesticides and herbicides, enhancing the effectiveness of these agricultural chemicals and contributing to more sustainable and efficient crop protection strategies.
Used in Coordination Chemistry:
As a potential ligand in coordination chemistry, 2-bromo-6-phenoxypyridine is employed to form coordination complexes with metal ions, which can exhibit unique properties and applications in various fields, such as catalysis, sensing, and materials science.

Upstream product

• 626-05-1 2,6-Dibromopyridine 
• 139-02-6 sodium phenoxide 
• 108-95-2 phenol 

Downstream Products

• 4783-68-0 2-phenoxypyridine 
• 68523-22-8 6-phenoxy-pyridin-2-ylcarboxaldehyde 
• 110628-68-7 1-(6-phenoxy-2-pyridinyl)-2,2,2-trifluoroethanone 
• 501378-40-1 6-phenoxypicolinonitrile 
• 51362-40-4 6-phenoxy-picolinic acid 

Relevant articles and documents

AMIDE COMPOUND AND PHARMACEUTICAL COMPRISING SAME

Provided is a novel compound which has an excellent Aβ aggregation inhibitory effect and is useful as a pharmaceutical. An amide compound represented by the formula (1) or a salt thereof, wherein Z represents CH or N; A and B are the same or different and each represents —CH2—, —O—, —S—, or —NH—; R1 and R2 are the same or different and each represents a branched alkyl group, a branched alkenyl group, an optionally substituted aromatic hydrocarbon group, an optionally substituted aralkyl group, an optionally substituted cycloalkyl group, or an optionally substituted aromatic heterocyclic group; and R3 represents a branched alkyl group, a branched alkenyl group, an optionally substituted cycloalkyl group, or an optionally substituted aralkyl group.

Rational design and identification of a non-peptidic aggregation inhibitor of amyloid-β based on a pharmacophore motif obtained from cyclo[-Lys-Leu-Val-Phe-Phe-]

Inhibition of pathogenic protein aggregation may be an important and straightforward therapeutic strategy for curing amyloid diseases. Small-molecule aggregation inhibitors of Alzheimer's amyloid-β (Aβ) are extremely scarce, however, and are mainly restricted to dye- and polyphenol-type compounds that lack drug-likeness. Based on the structure-activity relationship of cyclic Aβ16-20 (cyclo-[KLVFF]), we identified unique pharmacophore motifs comprising side-chains of Leu2, Val3, Phe4, and Phe5 residues without involvement of the backbone amide bonds to inhibit Aβ aggregation. This finding allowed us to design non-peptidic, small-molecule aggregation inhibitors that possess potent activity. These molecules are the first successful non-peptidic, small-molecule aggregation inhibitors of amyloids based on rational molecular design.

NOVEL ANTIMALARIA AGENT CONTAINING HETEROCYCLIC COMPOUND

Disclosed is an antimalarial agent containing a compound represented by the formula: [wherein A1 represents a 3-pyridyl group that may have a substituent, a 6-quinolyl group that may have a substituent, or the like; X1 represents a group represented by the formula -C(=O)-NH- or the like; E represents a furyl group, a thienyl group or a phenyl group; with the proviso that A1 may have one to three substituents, and E has one of two substituents] or a salt thereof or hydrates thereof.

NOVEL ANTIFUNGAL AGENT COMPRISING HETEROCYCLIC COMPOUND

The present invention provides an antifungal agent represented by the formula: [wherein A1 represents a 3-pyridyl group which may have a substituent, a quinolyl group which may have a substituent, or the like; X1 represents a group represented by the formula -NH-C(=O)-, a group represented by the formula -C(=O)-NH-, or the like; E represents a furyl group, a thienyl group, a pyrrolyl group, a phenyl group, a pyridyl group, a tetrazolyl group, a thiazolyl group or a pyrazolyl group; with the proviso that A1 may have 1 to 3 substituents, and E has one or two substituents].

Insecticidal and acaricidal phenoxypyrdinyl esters and intermediates

Insecticidal and acaricidal organic esters formed from pyrethroid carboxylic acids and phenoxypyridinyltrifluoroethanols, agricultural compositions containing said esters and their use against anthropod pests including soil-dwelling species; also, intermediates for these insecticides and acaricides and a process for the preparation of said intermediates.