Welcome to LookChem.com Sign In|Join Free

Cas Database

84624-28-2

84624-28-2

Identification

  • Product Name:N'-Fmoc-L-lysine

  • CAS Number: 84624-28-2

  • EINECS:

  • Molecular Weight:368.433

  • Molecular Formula: C21H24N2O4

  • HS Code:2924297099

  • Mol File:84624-28-2.mol

Synonyms:3: PN:WO03068990 PAGE: 60 claimed sequence;H-Lys(Fmoc)-OH;

Post Buying Request Now

Safety information and MSDS view more

  • Signal Word:Warning

  • Hazard Statement:H400 Very toxic to aquatic life

  • First-aid measures: General adviceConsult a physician. Show this safety data sheet to the doctor in attendance.If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

  • Fire-fighting measures: Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.

  • Accidental release measures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

  • Handling and storage: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

  • Exposure controls/personal protection:Occupational Exposure limit valuesBiological limit values Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Eye/face protection Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Respiratory protection Wear dust mask when handling large quantities. Thermal hazards

Supplier and reference price view more

  • Manufacture/Brand
  • Product Description
  • Packaging
  • Price
  • Delivery
  • Purchase
  • Manufacture/Brand:TRC
  • Product Description:Nε-Fmoc-L-lysine
  • Packaging:500mg
  • Price:$ 120
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Medical Isotopes, Inc.
  • Product Description:(S)-6-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-aminohexanoicacid 95+%
  • Packaging:1 g
  • Price:$ 325
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Iris Biotech GmbH
  • Product Description:H-L-Lys(Fmoc)-OH
  • Packaging:1 g
  • Price:$ 94.5
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Iris Biotech GmbH
  • Product Description:H-L-Lys(Fmoc)-OH
  • Packaging:5 g
  • Price:$ 236.25
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Crysdot
  • Product Description:H-Lys(Fmoc)-OH 95+%
  • Packaging:100g
  • Price:$ 376
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:ChemScene
  • Product Description:H-Lys(Fmoc)-OH
  • Packaging:25g
  • Price:$ 114
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:ChemScene
  • Product Description:H-Lys(Fmoc)-OH
  • Packaging:10g
  • Price:$ 51
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:ChemScene
  • Product Description:H-Lys(Fmoc)-OH
  • Packaging:5g
  • Price:$ 31
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:ChemScene
  • Product Description:H-Lys(Fmoc)-OH
  • Packaging:100g
  • Price:$ 385
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Chem-Impex
  • Product Description:Nε-Fmoc-L-lysine,99%(HPLC) 99%(HPLC)
  • Packaging:25G
  • Price:$ 599.2
  • Delivery:In stock
  • Buy Now

Relevant articles and documentsAll total 8 Articles be found

Method for selective structural modification of L-lysine

-

Paragraph 0025; 0053-0057, (2020/07/15)

The invention belongs to the field of chemical synthesis, and particularly relates to a method for selective structural modification of L-lysine. According to a specific technical scheme in the invention, L-lysine is taken as a raw material, silicon dioxide nanoparticles surface-functionalized by beta-cyclodextrin are taken as a catalyst, water is taken as a solvent, and a reaction is performed for 3-5 hours at 25 DEG C in the presence of an amino protective agent to obtain a final product of the reaction; the final reaction product is subjected to standing, and an upper-layer product is takenand subjected to washing, separating and filtering to obtain selectively-modified L-lysine. The used catalyst is odorless and non-toxic; the synthesis method is simple; catalytic performance is excellent; product separation is easy; the catalyst can be repeatedly used; the method effectively solves the problem that a mixture of a common beta-cyclodextrin catalyzed product and cyclodextrin floatson a liquid level and is difficult to separate, simplifies post-treatment steps, reduces the use amount of an organic solvent, and greatly reduces the amount of waste liquid generated in the stage ofpurification.

Decomposition of copper-amino acid complexes by sodium sulfide

Nowshuddin, Shaik,Reddy, A. Ram

, p. 5159 - 5161 (2007/10/03)

Sodium sulfide very efficiently removes copper from protected amino acid-copper complexes. The copper in the amino acid complex was reduced to insoluble cuprous sulfide and the free amino acid was released in pure form. This method is very convenient and rapid, requiring only 5-10 min and 0.55-0.75 equiv of sodium sulfide.

Chemistry in living cells: Detection of active proteasomes by a two-step labeling strategy

Ovaa, Huib,Van Swieten, Paul F.,Kessler, Benedikt M.,Leeuwenburgh, Michiel A.,Fiebiger, Edda,Van den Nieuwendijk, Adrianus M. C. H.,Galardy, Paul J.,Van der Marel, Gijsbert A.,Ploegh, Hidde L.,Overkleeft, Herman S.

, p. 3626 - 3629 (2007/10/03)

In vivo targeting of the proteasome: Probe 1 is a cell-permeable irreversible inhibitor that alkylates the active-site residues of the proteasome in a Michael fashion. After cell lysis, a biotin moiety is introduced by Staudinger ligation to yield construct 2. This strategy allows activity profiling of the catalytic activities of the proteasome in vivo.

Process route upstream and downstream products

Process route

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide
82911-69-1

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

N-(fluorenyl-9-methoxycarbonyl)-L-lysine
84624-28-2,212140-39-1

N-(fluorenyl-9-methoxycarbonyl)-L-lysine

Conditions
Conditions Yield
L-lysine; With sodium carbonate; In water; for 1h; pH=Ca. 9;
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide; In water; at 25 ℃; for 5h;
18.3%
Boc-Lys(Fmoc)-OH
84624-27-1

Boc-Lys(Fmoc)-OH

N-(fluorenyl-9-methoxycarbonyl)-L-lysine
84624-28-2,212140-39-1

N-(fluorenyl-9-methoxycarbonyl)-L-lysine

Conditions
Conditions Yield
With trifluoroacetic acid; In dichloromethane;
92%
copper(II); 2-amino-6-(9<i>H</i>-fluoren-9-ylmethoxycarbonylamino)-hexanoate

copper(II); 2-amino-6-(9H-fluoren-9-ylmethoxycarbonylamino)-hexanoate

N-(fluorenyl-9-methoxycarbonyl)-L-lysine
84624-28-2,212140-39-1

N-(fluorenyl-9-methoxycarbonyl)-L-lysine

Conditions
Conditions Yield
With sodium sulfide; In water; at 25 - 30 ℃; for 0.166667h;
96%
C<sub>42</sub>H<sub>46</sub>CuN<sub>4</sub>O<sub>8</sub>

C42H46CuN4O8

N-(fluorenyl-9-methoxycarbonyl)-L-lysine
84624-28-2,212140-39-1

N-(fluorenyl-9-methoxycarbonyl)-L-lysine

Conditions
Conditions Yield
With hydrogenchloride; oxalic acid; In water; at 80 ℃; pH=1.1;
69%
6-(9<i>H</i>-fluoren-9-ylmethoxycarbonylamino)-2-[2-(4-trifluoromethyl-benzenesulfonyl)-ethoxycarbonylamino]-hexanoic acid methyl ester
849752-39-2

6-(9H-fluoren-9-ylmethoxycarbonylamino)-2-[2-(4-trifluoromethyl-benzenesulfonyl)-ethoxycarbonylamino]-hexanoic acid methyl ester

N-(fluorenyl-9-methoxycarbonyl)-L-lysine
84624-28-2,212140-39-1

N-(fluorenyl-9-methoxycarbonyl)-L-lysine

N<sub>ε</sub>-<(fluoren-9-ylmethoxy)carbonyl>lysine methyl ester
133628-29-2

Nε-<(fluoren-9-ylmethoxy)carbonyl>lysine methyl ester

Conditions
Conditions Yield
With lithium hydroxide; In tetrahydrofuran; water; at 0 ℃; for 0.0833333h;
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide
82911-69-1

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

L-lysine dihydrochloride
657-26-1,26124-78-7

L-lysine dihydrochloride

N-(fluorenyl-9-methoxycarbonyl)-L-lysine
84624-28-2,212140-39-1

N-(fluorenyl-9-methoxycarbonyl)-L-lysine

Conditions
Conditions Yield
With sodium carbonate; Yield given. Multistep reaction; 1.) H2O, 2.) 1,2-dimethoxyethane, H2O;
N<sup>ε</sup>-(9-fluorenylmethoxycarbonyl)-L-lysine methyl ester hydrochloride
201009-98-5

Nε-(9-fluorenylmethoxycarbonyl)-L-lysine methyl ester hydrochloride

N-(fluorenyl-9-methoxycarbonyl)-L-lysine
84624-28-2,212140-39-1

N-(fluorenyl-9-methoxycarbonyl)-L-lysine

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: 92 percent / triethylamine / CH2Cl2 / 0 - 20 °C
2: LiOH / tetrahydrofuran; H2O / 0.08 h / 0 °C
With lithium hydroxide; triethylamine; In tetrahydrofuran; dichloromethane; water;
(fluorenylmethoxy)carbonyl chloride
28920-43-6

(fluorenylmethoxy)carbonyl chloride

L-Lysine hydrochloride
657-27-2,10098-89-2,26124-78-7

L-Lysine hydrochloride

N-(fluorenyl-9-methoxycarbonyl)-L-lysine
84624-28-2,212140-39-1

N-(fluorenyl-9-methoxycarbonyl)-L-lysine

Conditions
Conditions Yield
With sodium hydroxide; ethylenediaminetetraacetic acid; sodium hydrogencarbonate; copper(II) sulfate; Yield given. Multistep reaction;
(9H-fluoren-9-yl)methyl azidoformate
28920-44-7

(9H-fluoren-9-yl)methyl azidoformate

L-Lysine hydrochloride
657-27-2,10098-89-2,26124-78-7

L-Lysine hydrochloride

N-(fluorenyl-9-methoxycarbonyl)-L-lysine
84624-28-2,212140-39-1

N-(fluorenyl-9-methoxycarbonyl)-L-lysine

Conditions
Conditions Yield
Yield given. Multistep reaction;
N-(fluoren-9-ylmethoxycarbonyl)glycine
29022-11-5

N-(fluoren-9-ylmethoxycarbonyl)glycine

N-(fluorenyl-9-methoxycarbonyl)-L-lysine
84624-28-2,212140-39-1

N-(fluorenyl-9-methoxycarbonyl)-L-lysine

N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serine
73724-45-5

N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serine

C<sub>46</sub>H<sub>82</sub>N<sub>18</sub>O<sub>15</sub>
1035896-23-1

C46H82N18O15

Conditions
Conditions Yield
Multistep reaction.;

Global suppliers and manufacturers

Global( 65) Suppliers
  • Company Name
  • Business Type
  • Contact Tel
  • Emails
  • Main Products
  • Country
  • Simagchem Corporation
  • Business Type:Manufacturers
  • Contact Tel:+86-592-2680277
  • Emails:sale@simagchem.com
  • Main Products:110
  • Country:China (Mainland)
  • Shanghai Upbio Tech Co.,Ltd
  • Business Type:Lab/Research institutions
  • Contact Tel:+86-21-52196435
  • Emails:upbiocn@hotmail.com
  • Main Products:89
  • Country:China (Mainland)
  • Win-Win chemical Co.Ltd
  • Business Type:Lab/Research institutions
  • Contact Tel:0086-577-64498589
  • Emails:sales@win-winchemical.com
  • Main Products:55
  • Country:China (Mainland)
  • Kono Chem Co.,Ltd
  • Business Type:Other
  • Contact Tel:86-29-86107037-8015
  • Emails:info@konochemical.com
  • Main Products:82
  • Country:China (Mainland)
  • Hangzhou Dingyan Chem Co., Ltd
  • Business Type:Manufacturers
  • Contact Tel:86-571-86465881,86-571-87157530,86-571-88025800
  • Emails:sales@dingyanchem.com
  • Main Products:95
  • Country:China (Mainland)
close
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 84624-28-2
Post Buying Request Now
close
Remarks: The blank with*must be completed