85657-94-9

Basic information

• Product Name: Acetamide, N-(3,5-dimethoxyphenyl)-2,2,2-trifluoro-
• CAS NO: 85657-94-9
• Molecular Formula: C10H10F3NO3
• Molecular Weight: 249.19
• Mol File: 85657-94-9.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Acetamide, N-(3,5-dimethoxyphenyl)-2,2,2-trifluoro-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-(3,5-dimethoxyphenyl)-2,2,2-trifluoro-(85657-94-9)
• EPA Substance Registry System: Acetamide, N-(3,5-dimethoxyphenyl)-2,2,2-trifluoro-(85657-94-9)

Safety Data

• Hazardous Substances Data: 85657-94-9(Hazardous Substances Data)

Upstream product

• 75996-26-8 azido(3,5-dimethoxyphenyl)methanone 
• 76-05-1 trifluoroacetic acid 
• 1132-21-4 3,5-dimethoxybenzoic acid 
• 99-10-5 3,5-Dihydroxybenzoic acid 
• 383-63-1 ethyl trifluoroacetate, 
• 10272-07-8 3.5-dimethoxyaniline 
• 17213-57-9 3,5-dimethoxybenzoyl chloride 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 1599437-13-4 N-(2-bromo-3,5-dimethoxybenzene)-2,2,2-trifluoroacetamide 
• 63920-73-0 2-amino-4,6-dimethoxybenzamide 
• 1044870-30-5 2-(4-hydroxy-3,5-dimethylphenyl)-5,7-dimethoxy-3,4-dihydroquinazolin-4-one 
• 1044870-39-4 2-(4-(2-hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethoxy-3,4-dihydroquinazoline-4-one 
• 1599437-15-6 2,4-dibromo-3,5-dimethoxytrifluoroacetanilide 
• 1603827-26-4 C₁₀H₉BrF₃NO₃ 
• 1603827-27-5 C₁₀H₈Br₂F₃NO₃ 
• 1545025-44-2 2-amino-4,6-dimethoxybenzonitrile 
• 1378670-58-6 C₉H₁₀N₂O₂ 
• 429681-68-5 N-(4-acetyl-3,5-dimethoxyphenyl)trifluoroacetamide 
• 1026932-90-0 benzoic acid 2-acetyl-3-methoxy-5-(2,2,2-trifluoro-acetylamino)-phenyl ester 
• 429681-70-9 N-(4-acetyl-3-hydroxy-5-methoxyphenyl)trifluoroacetamide 
• 429681-67-4 N-(2-acetyl-3,5-dimethoxyphenyl)trifluoroacetamide 

Relevant articles and documents

Design, synthesis and biological evaluation of hypolipidemic compounds based on BRD4 inhibitor RVX-208

Bromodomain-containing protein 4 (BRD4) is a new therapeutic target for the treatment of diseases including cardiovascular diseases, cancer, inflammation and central nervous system (CNS) disorders. In this study, we introduced the pharmacophore of fibrates to a BRD4 inhibitor, RVX-208, to design dual-active hypolipidemic compounds, and found that some of new analogues showed favorable hypolipidemic activities. Synthetic accessibility towards this class of compounds optimized RVX-208 as well as would supply more thoughts on hypolipidemic drugs.

PROCESSES FOR THE SYNTHESIS OF 2-AMINO-4,6-DIMETHOXYBENZAMIDE AND OTHER BENZAMIDE COMPOUNDS

This invention provides a method for the synthesis of a 2-amino-4,6-dimethoxybenzamide and other benzamides of Compound I: wherein R1, R2, R3, and R4 each independently represent a hydrogen, a C1-C6 alkyl, or a C1-C6 alkoxy; and wherein R6 and R7 each independently represent a hydrogen, a C1-C6 alkyl, a protecting group, or a directing group.

CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT

Novel cromolyn analogs useful as imaging agents for detecting atherosclerotic plaques and for treating atherosclerosis and Alzheimer's Disease, and methods of making the cromolyn analogs, are disclosed. The cromolyn analogs have the general formula (I), o