85995-49-9Relevant articles and documents
Conversion of Formamides to Alcohols via N-Nitrosation
Iwata, Masaaki,Kuzuhara, Hiroyoshi
, p. 1195 - 1198 (2007/10/02)
Secondary formamides were found to be favorable sources for the efficient oxygenation site via N-nitrosation.Thermal reaction (85 deg C in benzene) of N-nitrozo formamides proceeded effectively to provide the corresponding formates in good yields, which, then, were hydrolyzed to alcohols under weakly basic conditions.In treatment of optically active formamide, the corresponding alcohol was isolated with 72percent retention of configuration.