95-41-0Relevant articles and documents
Catalytic intermolecular Pauson-Khand-type reaction: Strong directing effect of pyridylsilyl and pyrimidylsilyl groups and isolation of Ru complexes relevant to catalytic reaction
Itami, Kenichiro,Mitsudo, Koichi,Fujita, Kazuyoshi,Ohashi, Youichi,Yoshida, Jun-Ichi
, p. 11058 - 11066 (2007/10/03)
Some circumstantial evidence for the directing effect of the 2-pyhdylsilyl group in the Ru-catalyzed intermolecular Pauson-Khand-type reaction (PKR) of alkenyl(2-pyridyl)silane, alkyne, and carbon monoxide has been provided. Most importantly, we have succeeded in isolating several monometallic Ru complexes relevant to the catalytic reaction: Ru(vinylsilane)(CO)3 complexes and ruthenacyclopentene. While the stoichimetric reaction of the Ru(vinylsilane)(CO)3 complex with an alkyne led to the formation of the corresponding cyclopentenone (PKR product) at 100 °C, the ruthenacyclopentene intermediate was quantitatively produced at 50 °C. This complex was also converted to a cyclopentenone upon heating at 100 °C. Moreover, it was also found that the Ru(vinylsilane)(CO)3 complex and ruthenacyclopentene serve as catalysts in intermolecular PKR.
Carbonyl compounds, methods of making the same, and their use as fragrances and fragrance-enhancing additives
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, (2008/06/13)
Carbonyl compounds derived from the reaction of alkyl cyclopentenols and vinyl ethers are described. The carbonyl compounds described have excellent fragrance properties, and their use as fragrances and/or fragrance-enhancing compounds is also described. Processes for the preparation of the carbonyl compounds are described as well.
Serine carbonates
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, (2008/06/13)
Serine carbonates of formula I are precursors for organoleptic compounds, masking agents and antimicrobial agents. Further they are alternative substrates for malodor producing enzymes. The symbols in formula I are defined in claim 1.
Process for producing 2-alkyl-2cyclopentenones
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, (2008/06/13)
Industrially advantageous processes for producing a 2-alkyl-2-cyclopentenone in high yields starting from a 2-(1-hydroxyalkyl)cyclopentanone or a 2-alkylidenecyclopentanone, which are obtainable from a cyclopentanone and a carbonyl compound. A 2-(1-hydroxyalkyl)cyclopentanone represented by the following general formula (1): (wherein R1, R2, R3, R4, R5, R6 and R7 each independently represents hydrogen atom, an alkyl group having 1 to 10 carbon atoms which may have one or more substituents or an aromatic group which may have one or more substituents, and each of (1) R6 or R7 with R3 and (2) R6 or R7 with R4 or R5 may be together combined to form a ring which may have a double bond) is subjected to dehydrative isomerization in the presence of a bromine compound and/or an iodine compound.
A pyridylsilyl group expands the scope of catalytic intermolecular Pauson-Khand reactions
Itami, Kenichiro,Mitsudo, Koichi,Yoshida, Jun-Ichi
, p. 3481 - 3484 (2007/10/03)
Now even unstrained alkenes can be used in catalytic intermolecular Pauson-Khand reactions [Eq. (a)]. This is made possible by the use of the directing group dimethyl(2-pyridyl)silyl, which can be easily removed at the end of the reaction. Furthermore, one observes completely regioselective incorporation of substituents at the 4- and 5-positions of the 2-cyclopentenone structure.
Compounds having protected hydroxy groups
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, (2008/06/13)
The present invention relates to compounds with protected hydroxy groups of formula (I) These compounds are precursors for organoleptic agents, such as fragrances, and masking agents and for antimicrobial agents. When activated, the compounds of formula (I) are cleaved and form one or more organoleptic and/or antimicrobial compounds.
Compounds having protected hydroxy groups
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, (2008/06/13)
The present invention relates to compounds with protected hydroxy groups of formula (I) These compounds are precursors for organoleptic agents, such as fragrances, and masking agents and for antimicrobial agents. When activated, the compounds of formula (I) are cleaved and form one or more organoleptic and/or antimicrobial compounds.
Precursors for fragrant ketones and fragrant aldehydes
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, (2008/06/13)
The present invention refers to fragrance precursors of formula I for a fragrant ketone of formula II and one or more fragrant aldehydes or ketones of formula III and IV, These fragrance precursors are useful in perfumery, especially in the fine and functional perfumery.
Beta-ketoester compounds
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, (2008/06/13)
The beta-ketoesters of formula I are useful as precursors for organoleptic compounds, especially for flavors, fragrances and masking agents and antimicrobial compounds.
Ketone precursors for organoleptic compounds
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, (2008/06/13)
The invention discloses ketones of formula I: wherein, Y is an optionally substituted alkyl, cycloalkyl, or cycloalkylalkyl, wherein each alkyl group is straight or branched and each alkyl and cycloalkyl group is saturated or unsaturated; R1is hydrogen or a C1-6alkyl group that is substituted, saturated or unsaturated, straight or branched; A is a chromophoric substituted aromatic ring or ring system; n is an integer; and with the proviso that formula I is not 2-ethoxy-1-phenyl-ethanone. These compositions are useful for the delivery of organoleptic compounds, especially of flavors, fragrances, masking agents and antimicrobial compounds.
