950-59-4

Basic information

• Product Name: 2,6-Di-tert-butyl-4-mercaptophenol
• Synonyms: 2,6-DI-TERT-BUTYL-4-THIOPHENOL;2,6-Di-tert-butyl-4-mercaptophenol;2,6-ditert-butyl-4-sulfanylphenol;2,6-ditert-butyl-4-sulfanyl-phenol;4-Mercapto-2,6-di-tert-butylphenol
• CAS NO: 950-59-4
• Molecular Formula: C₁₄H₂₂OS
• Molecular Weight: 238.39
• EINECS: 213-451-5
• Product Categories: Phenol&Thiophenol&Mercaptan
• Mol File: 950-59-4.mol
• Article Data: 28

Chemical Properties

• Boiling Point: 302.2 °C at 760 mmHg
• Flash Point: 136.6 °C
• Appearance: /
• Density: 1.019 g/cm³
• Vapor Pressure: 0.000559mmHg at 25°C
• Refractive Index: 1.537
• Solubility: Dichloromethane, Diethylether, Ethyl Acetate, Hexanes
• CAS DataBase Reference: 2,6-Di-tert-butyl-4-mercaptophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Di-tert-butyl-4-mercaptophenol(950-59-4)
• EPA Substance Registry System: 2,6-Di-tert-butyl-4-mercaptophenol(950-59-4)

Safety Data

• Hazardous Substances Data: 950-59-4(Hazardous Substances Data)

Usage

Uses

A possible inhibitor of DNA-benzo[a]pyrene adducts formation and benzopyrene activation.

InChI:InChI=1/C14H22OS/c1-13(2,3)10-7-9(16)8-11(12(10)15)14(4,5)6/h7-8,15-16H,1-6H3

Upstream product

• 128-39-2 2,6-di-tert-butylphenol 
• 3957-71-9 3,5-di-tert-butyl-4-hydroxyphenylthiocyanate 
• 6386-58-9 4,4'-dithiobis(2,6-di-tert-butylphenol) 

Downstream Products

• 143745-66-8 2,6-bis(1,1-dimethylethyl)-4-<<2-(phenylamino)ethyl>thio>phenol 
• 27434-52-2 1,1-Bis(3,5-di-tert-butyl-4-hydroxyphenylthio)cyclohexane 
• 113206-81-8 4-(3,5-Di-tert-butyl-4-hydroxy-phenylsulfanyl)-butyric acid ethyl ester 
• 1028291-54-4 (3,5-Di-tert-butyl-4-hydroxy-phenylsulfanyl)-acetic acid tert-butyl ester 
• 223133-29-7 4-(3,5-di-t-butyl-4-hydroxyphenylthio)-2-(N-t-butoxycarbonyl-N-methylamino)nitrobenzene 
• 105077-26-7 3-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-N-(2,6-dimethylphenyl)propanamide 
• 108-95-2 phenol 
• 143418-04-6 methyl (2R)-2-(3,5-di-t-butyl-4-hydroxyphenyl)thiopropanoate 
• 139981-10-5 4,4'-[(Dimethylsilylene)bis(methylenethio)]-bis[2,6-di-t-butyl]phenol 
• 55109-77-8 2,6-bis(1,1-dimethylethyl)-4-[(2-hydroxyethyl)thio]-phenol 
• 138752-87-1 (+/-)2,6-bis(1,1-dimethylethyl)-4-[(2S*-hydroxy-1R*-methylpropyl)-thio]phenol 
• 173375-13-8 2-(4-hydroxy-3,5-di-tert-butylphenylthio)-4,6-dichloro-sym-triazine 

Relevant articles and documents

Synthesis method of dithiobis-butyl phenol and analogue thereof

The invention provides a synthesis method of dithiobis-butyl phenol and an analogue thereof. The synthesis method provided by the invention has the advantages of few steps, high yield and high purity of the obtained product. The dithiobis-butyl phenol and the analogue thereof synthesized by the invention can be used for preparing medicines for preventing and/or treating coronavirus pneumonia (containing COVID-19).

Chemo- and product-selective electrooxidation of 3-(arylthiomethyl)- Δ3-cephems

Electrolysis of 3-arylthiomethyl-Δ3-cephems possessing various substituents on the arylthio moiety undergo chemo selective and product-selective electrooxidation to give several different products. These include isomeric mixtures of the corresponding methoxylated cephems, a bis[(Δ3-cephem-3-yl)methyl]disulfide or a 3-dimethoxymethyl- Δ3-cephem. The selectivity of the oxidation is highly dependent on the nature of the substituents on the arylthio moiety which suggests that both steric and electronic effects play an important role in the electrooxidation of 3-arylthiomethyl-Δ3-cephems.

COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISORDERS

The present invention relates to compounds and methods for the treatment of cardiovascular diseases and disorders. Compounds according to the present invention may comprise an optionally substituted phenyl ring linked to an aromatic or alkyl group by a spacer, wherein the spacer comprises two groups selected from selenium, sulfur, S(O) and S(O)2 and may further optionally comprise an alkylene, alkenylene, cycloalkylene or arylene moiety between the respective selenium, sulfur, S(O) and S(O)2 groups.