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Carteolol hydrochloride
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Name

Carteolol hydrochloride

 EINECS N/A
CAS No. 51781-21-6 Density 1.13g/cm3
PSA 70.59000 LogP 3.03000
Solubility N/A Melting Point 278°C
Formula C16H24 N2 O3 . Cl H Boiling Point 518.6°Cat760mmHg
Molecular Weight 328.839 Flash Point 267.4°C
Transport Information N/A Appearance N/A
Safety Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl. Risk Codes N/A
Molecular Structure Molecular Structure of 51781-21-6 (2(1H)-QUINOLINONE, 5-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-3,4-DIHYDRO-, MONOHYDROCHLORIDE) Hazard Symbols N/A
Synonyms

2(1H)-Quinolinone,5-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-,monohydrochloride (9CI);5-(3-tert-Butylamino-2-hydroxy)propoxy-3,4-dihydrocarbostyril hydrochloride;Arteoptic; Caltidren; Carteol; Carteolol hydrochloride; Cartrol; Endak;Mikelan; NSC 300906; OC 1085; OPC 1085; Ocupress; Optipress; Tenalet; Tenalin;Teoptic; dl-Carteolol hydrochloride

Article Data 3

Carteolol hydrochloride Chemical Properties

The IUPAC name of Carteolol hydrochloride (CAS NO.51781-21-6):
5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-
Synonyms: 5-(2-Hydroxy-3-tert-butylamino)propoxy-3,4-dihydrocarbostyrilhydrochloride ; 5-(3-((1,1-Dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-2(1h)-quinolin ; 5-(3-Tert-butylamino-2-hydroxy)propoxy-3,4-dihydrocarbostyrilhydrochloride ; 5-(3-Tert-butylamino-2-hydroxy-propoxy)-3,4-dihydro-2(1h)-chinolinon-hydroch ; Abbott-43326 ; Carbonolol ; Carteololhydrochloride ; Endak
CAS: 51781-21-6 
EINECS: 257-415-7
Molecular Formula: C16H25ClN2O3 
Molecular Structure:

Formula Weight: 328.83 
Flash Point: 267.4 °C 
Boiling Point: 518.6 °C at 760 mmHg 
Melting point:278°C 

Carteolol hydrochloride Toxicity Data With Reference

The toxicity of Carteolol hydrochloride (CAS NO.51781-21-6): 

1.    

orl-rat LD50:1330 mg/kg

     OYYAA2    Oyo Yakuri. Pharmacometrics. 11 (1976),159.
2.    

ipr-rat LD50:390 mg/kg

     OYYAA2    Oyo Yakuri. Pharmacometrics. 11 (1976),159.
3.    

scu-rat LD50:1950 mg/kg

     OYYAA2    Oyo Yakuri. Pharmacometrics. 11 (1976),159.
4.    

ivn-rat LD50:153 mg/kg

     OYYAA2    Oyo Yakuri. Pharmacometrics. 11 (1976),159.
5.    

orl-mus LD50:810 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 33 (1983),290.
6.    

ipr-mus LD50:375 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 33 (1983),290.
7.    

scu-mus LD50:600 mg/kg

     IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 12 (1981),668.
8.    

ivn-mus LD50:54,500 µg/kg

     IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 12 (1981),668.
9.    

orl-dog LD50:830 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 33 (1983),290.
10.    

orl-rbt LD50:740 mg/kg

     OYYAA2    Oyo Yakuri. Pharmacometrics. 11 (1976),165.

Carteolol hydrochloride Consensus Reports

EPA Genetic Toxicology Program.

Carteolol hydrochloride Safety Profile

The safety information of Carteolol hydrochloride (CAS NO.51781-21-6):
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl.

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