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Carteolol

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Name

Carteolol

EINECS N/A
CAS No. 51781-06-7 Density 1.13 g/cm3
PSA 70.59000 LogP 2.22800
Solubility N/A Melting Point N/A
Formula C16H24 N2 O3 Boiling Point 518.6 °C at 760 mmHg
Molecular Weight 292.378 Flash Point 267.4 °C
Transport Information N/A Appearance N/A
Safety Poison by intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx. Risk Codes N/A
Molecular Structure Molecular Structure of 51781-06-7 (5-[3-(tert-Butylamino)-2-hydroxypropoxy]-3,4-dihydro-1H-quinolin-2-one) Hazard Symbols N/A
Synonyms

(?à)-Carteolol; Carteolol;dl-Carteolol

Article Data 9

Carteolol Chemical Properties

Chemistry informtion about Carteolol (CAS NO.51781-06-7) is:
IUPAC Name: 5-[3-(Tert-Butylamino)-2-Hydroxypropoxy]-3,4-Dihydro-1h-Quinolin-2-One
Synonyms: 2(1h)-Quinolinone, 5-[3-[(1,1-Dimethylethyl)Amino]-2-Hydroxypropoxy]-3,4-Dihydro- ; Carteolol ; 2(H)-Quinolinone, 5-[3-[(1,1-Dimethylethyl)Amino]-2-Hydroxypropoxy]-3,4-Dihydro- ; Dl-Carteolol ; Carteolol (Base And/Or Unspecified Salts) ; 5-[3-(Tert-Butylamino)-2-Hydroxypropoxy]-3,4-Dihydro-1h-Quinolin-2-One ; 5-(2-Hydroxy-3-Tert-Butylaminopropoxy)-3,4-Dihydro-2(1h)-Quinolone ; 5-[3-(Tert-Butylamino)-2-Hydroxypropoxy]-3,4-Dihydrocarbostyril
MF: C16H24N2O3
MW: 292.37 
Density: 1.13 g/cm3
Flash Point: 267.4 °C 
Boiling Point: 518.6 °C at 760 mmHg
Vapour Pressure: 1.4E-11 mmHg at 25°C 
Enthalpy of Vaporization: 83.29 kJ/mol
Following is the molecular structure of Carteolol (CAS NO.51781-06-7) is:

Carteolol Uses

 Carteolol (CAS NO.51781-06-7) is a non-selective beta blocker used to treat glaucoma.

Carteolol Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral 830mg/kg (830mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 323, 1980.
mouse LD50 oral 810mg/kg (810mg/kg)   Japanese Journal of Toxicology. Vol. 4, Pg. 121, 1991.
rabbit LD50 intravenous 112mg/kg (112mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 323, 1980.
rabbit LD50 oral 740mg/kg (740mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 323, 1980.

Carteolol Safety Profile

Poison by intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx.

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