Immunosuppressive drugs
Immunosuppressive drugs are medications that inhibit or suppress the activity of the immune system, used primarily to prevent the rejection of transplanted organs and tissues, and to treat autoimmune diseases where the immune system mistakenly attacks the body's own tissues. These drugs work through various mechanisms to reduce immune responses, such as by inhibiting the proliferation of immune cells, blocking specific immune pathways, or reducing the production of immune-related chemicals. Common immunosuppressive drugs include corticosteroids (like prednisone), which decrease inflammation and immune activity, calcineurin inhibitors (such as cyclosporine and tacrolimus), which block T-cell activation, and mTOR inhibitors (like sirolimus), which prevent immune cell proliferation. Additionally, biologic agents like monoclonal antibodies (such as rituximab) target specific components of the immune system to reduce immune responses. While highly effective in managing conditions that require immune suppression, these drugs increase the risk of infections and other complications due to the reduced ability of the immune system to respond to pathogens.
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