- Cyclobenzaprine
- Cyclobenzaprine hydrochloride
- 30355-60-31,3,5-Triazine-2,4-diamine,6-(chloromethyl)-N2-phenyl-
- 30357-42-71,3,5-Triazin-2-amine,4-methyl-N-(1,1,3,3-tetramethylbutyl)-6-(trichloromethyl)-
- 30357-83-61,3,5-Triazin-2-amine,4,6-dibromo-N-(4-chlorophenyl)-
- 30358-18-01,3,5-Triazin-2-amine,4-methoxy-6-(methylthio)-
- 30358-36-2Tetracyclo[5.2.1.02,6.03,5]dec-8-ene,(1α,2α,3β,5β,6α,7α)- (9CI)
- 30358-69-1Tetradecanoicacid, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-(acetyloxy)-3-formyl-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-ylester
- 30359-92-32,4-DIAMINO-6-(1,1,2,2-TETRACHLOROETHYL)-S-TRI*
- 30361-17-2D-Ribofuranose,2-C-methyl-, 2,3,5-tribenzoate
- 30361-19-4D-Ribofuranose,2-C-methyl-, 1,2,3,5-tetrabenzoate
- 30361-28-52,4-Octadienal,(2E,4E)-
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
Cyclobenzaprine |
EINECS | 206-145-8 |
| CAS No. | 303-53-7 | Density | 1.096 g/cm3 |
| PSA | 3.24000 | LogP | 5.35580 |
| Solubility | Soluble in water | Melting Point |
N/A |
| Formula | C20H21 N | Boiling Point | 405.9 °C at 760 mmHg |
| Molecular Weight | 275.393 | Flash Point | 177.8 °C |
| Transport Information | N/A | Appearance | Solid |
| Safety | Poison by ingestion, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
5H-Dibenzo[a,d]cycloheptene-D5,g-propylamine, N,N-dimethyl- (7CI,8CI);10,11-Dehydroamitriptyline;5-(3-Dimethylaminopropylidene)dibenzo[a,d]cycloheptatriene; 9715 R.P; Amrix;Cyclobenzaprine; MK 130; N,N-Dimethyl-5H-dibenzo[a,d]cycloheptene-D5,g-propylamine; Proheptatrien; Proheptatriene; RP 9715;Ro 4-1577; [3-(5-H-Dibenzo[a,d]cyclohepten-5-ylidene)propyl]dimethylamine |
Article Data | 12 |
Cyclobenzaprine Synthetic route
| Conditions | Yield |
|---|---|
| With sodium tetrahydroborate In water at 50 - 60℃; chemoselective reaction; | 92% |
| Conditions | Yield |
|---|---|
| (i) Mg, EtBr, (ii) /BRN= 743171/, (iii) aq. HCl, AcOH; Multistep reaction; |
- 18029-54-4
5-[3-(N,N-dimethylamino)propyl]-5H-dibenzo[a,d]cyclohepten-5-ol
- 303-53-7
Cyclobenzaprine
| Conditions | Yield |
|---|---|
| With acetic anhydride Heating; |
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: (i) Mg, (ii) /BRN= 743171/, THF 2: Ac2O / Heating View Scheme |
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: (i) Mg, (ii) /BRN= 743171/, THF 2: Ac2O / Heating View Scheme |
- 303-53-7
Cyclobenzaprine
- 17822-51-4
1-benzylidene-3-oxo-1-pyrazolidinium-2-ide
| Conditions | Yield |
|---|---|
| With tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; potassium carbonate In acetonitrile at 30℃; for 7h; Irradiation; Schlenk technique; Sealed tube; | 98% |
- 303-53-7
Cyclobenzaprine
- 16203-86-4
5-Allyliden-dibenzocyclohepten
| Conditions | Yield |
|---|---|
| (i) MeI, (ii) aq. NaOH; Multistep reaction; |
- 303-53-7
Cyclobenzaprine
- 541-41-3
chloroformic acid ethyl ester
- 16234-95-0
ethyl N-<3-(5H-dibenzocyclohepten-5-ylidene)propyl>-N-methylcarbamate
| Conditions | Yield |
|---|---|
| In benzene Heating; |
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: benzene / Heating 2: aq. KOH, triethylene glycol / 180 °C View Scheme |
- 506-68-3
bromocyane
- 420-04-2
CYANAMID
- 303-53-7
Cyclobenzaprine
- 2455-49-4
5-[3-(n-cyano-N-methyl)aminopropylidene]-5H-dibenzo[a,d]cycloheptene
| Conditions | Yield |
|---|---|
| In benzene |
Cyclobenzaprine Chemical Properties
Product Name: Cyclobenzaprine
Synonyms:Cyclobenzaprine ; Cyclobenzaprine HCL ; 10,11-Dehydroamitriptyline ; 1-Propanamine, 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl- ; 3-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamin ; 3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine ; 5-(3-Dimetilaminopropiliden)-5H-dibenzo-(a,d)-ciclopentene ; 5H-Dibenzo(a,d)cycloheptene-delta5,gamma-propylamine, N,N-dimethyl-
Molecular Structure of Proheptatriene (CAS NO.303-53-7) : 
Molecular Formula of Proheptatriene (CAS NO.303-53-7) : C20H21N
Molecular Weight of Proheptatriene (CAS NO.303-53-7) : 275.39
CAS NO: 303-53-7
EINECS 206-145-8
Flash Point: 263.3 °C
Enthalpy of Vaporization: 79.76 kJ/mol
Boiling Point: 511.8 °C at 760 mmHg
Vapour Pressure: 7.65E-11 mmHg at 25°C
Cyclobenzaprine Uses
Proheptatriene (CAS NO.303-53-7) is used to alleviate the local muscle spasm and its associated symptoms, such as pain, tenderness and limited mobility.
Cyclobenzaprine Toxicity Data With Reference
| 1. | orl-mus LD50:250 mg/kg | FRPPAO Farmaco, Edizione Pratica. 25 (1970),519. | ||
| 2. | ipr-mus LD50:90 mg/kg | JMCMAR Journal of Medicinal Chemistry. 6 (1963),338. | ||
| 3. | ivn-mus LD50:36 mg/kg | FRPPAO Farmaco, Edizione Pratica. 25 (1970),519. |
Cyclobenzaprine Consensus Reports
EPA Genetic Toxicology Program.
Cyclobenzaprine Safety Profile
Poison by ingestion, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.
What can I do for you?
Get Best Price
