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Diethyl dipropylmalonate

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Name

Diethyl dipropylmalonate

EINECS 227-998-2
CAS No. 6065-63-0 Density 0.976 g/cm3
PSA 52.60000 LogP 2.69920
Solubility Melting Point N/A
Formula C13H24 O4 Boiling Point 262.9 °C at 760 mmHg
Molecular Weight 244.331 Flash Point STABILITY
Transport Information 200kgs Appearance Clear liquid
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 6065-63-0 (Diethyl dipropylmalonate) Hazard Symbols UN NO.
Synonyms

Malonicacid, dipropyl-, diethyl ester (7CI,8CI); Propanedioic acid, dipropyl-, diethylester (9CI); Diethyl 2,2-dipropylmalonate; Diethyl dipropylmalonate; NSC 163902

Article Data 13

Diethyl dipropylmalonate Synthetic route

3195-24-2

diallylmalonic acid diethyl ester

6065-63-0

2,2-dipropyl-malonic acid diethyl ester

Conditions
ConditionsYield
With 6C53H32O8(4-)*13Zr(4+)*18O(2-)*8Co(2+)*8H(1-); hydrogen In tetrahydrofuran at 23℃; under 30003 Torr; for 36h; Catalytic behavior; Mechanism; Reagent/catalyst;100%
With sodium tetrahydroborate; ruthenium trichloride In tetrahydrofuran; water at 20℃; for 1h;93%
With 6C53H32O8(4-)*13Zr(4+)*18O(2-)*8Co(2+)*8Cl(1-); hydrogen; sodium triethylborohydride In tetrahydrofuran at 23℃; under 30402 Torr; for 36h; Catalytic behavior; Time; Glovebox; Inert atmosphere;100 %Spectr.
With fac-[Mn(1,2-bis(di-isopropylphosphino)ethane)(CO)3(CH2CH2CH3)]; hydrogen In diethyl ether at 25℃; under 37503.8 Torr; for 18h;75 %Chromat.
With hydrogen In water at 60℃; under 22502.3 Torr; for 18h; Autoclave; Green chemistry;
1439866-82-6

diethyl 2-(3-iodopropyl)-2-propylmalonate

6065-63-0

2,2-dipropyl-malonic acid diethyl ester

Conditions
ConditionsYield
With [Ir(2-phenylpyridine)-2-(4,4’-di-tert-butyl-2,2’-bipyridine)]PF6; N-ethyl-N,N-diisopropylamine In acetonitrile at 25℃; for 5h; Irradiation;88%
106-94-5

propyl bromide

2163-48-6

diethyl propylmalonate

6065-63-0

2,2-dipropyl-malonic acid diethyl ester

Conditions
ConditionsYield
With sodium ethanolate In ethanol for 10h; Heating;83%
107-08-4

1-iodo-propane

2163-48-6

diethyl propylmalonate

6065-63-0

2,2-dipropyl-malonic acid diethyl ester

Conditions
ConditionsYield
With caesium carbonate In butanone at 70℃; for 15h;70%
106-94-5

propyl bromide

105-53-3

diethyl malonate

A

6065-63-0

2,2-dipropyl-malonic acid diethyl ester

B

616-62-6

n-propylmalonic acid

Conditions
ConditionsYield
With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride for 16h;A 48%
B 41%
107-08-4

1-iodo-propane

105-53-3

diethyl malonate

6065-63-0

2,2-dipropyl-malonic acid diethyl ester

Conditions
ConditionsYield
With zinc
107-08-4

1-iodo-propane

105-53-3

diethyl malonate

A

6065-63-0

2,2-dipropyl-malonic acid diethyl ester

B

2163-48-6

diethyl propylmalonate

Conditions
ConditionsYield
With zinc
107-08-4

1-iodo-propane

105-53-3

diethyl malonate

A

6065-63-0

2,2-dipropyl-malonic acid diethyl ester

B

2163-48-6

diethyl propylmalonate

105-53-3

diethyl malonate

6-ethoxy-4-cyano-5-methyl-hex-2ξ-enoic acid ethyl ester

6-ethoxy-4-cyano-5-methyl-hex-2ξ-enoic acid ethyl ester

6065-63-0

2,2-dipropyl-malonic acid diethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 93 percent / NaOEt / ethanol / 7 h / Heating
2: 83 percent / NaOEt / ethanol / 10 h / Heating
View Scheme
101268-55-7

4,4-bis(ethoxycarbonyl)-1-hepten-6-yne

A

6065-63-0

2,2-dipropyl-malonic acid diethyl ester

B

1114376-78-1

diethyl cis-3,4-dimethylcyclopentane-1,1-dicarboxylate

diethyl (3R,4R)-3,4-dimethylcyclopentane-1,1-dicarboxylate

Conditions
ConditionsYield
With (IPr2,6-(2,6-iPr2C6H3N=CMe)2C5H3N)Fe(N2)2; hydrogen In benzene at 23℃; under 3040.2 Torr; for 3h; Inert atmosphere; optical yield given as %de;A 25.9 %Chromat.
B n/a
C n/a

Diethyl dipropylmalonate Chemical Properties

Molecular Structure:

Molecular Formula: C13H24O4
Molecular Weight: 244.3273
IUPAC Name: Diethyl 2,2-dipropylpropanedioate
Synonyms of Propanedioic acid,2,2-dipropyl-, 1,3-diethyl ester (CAS NO.6065-63-0): EINECS 227-998-2 ; Diethyl dipropylmalonate
CAS NO: 6065-63-0
Classification Code: Pharmaceutical Intermediates ; TheMalonateRamificationProducts
Index of Refraction:  1.438 
Molar Refractivity:  65.79 cm3 
Molar Volume:  250.1 cm3 
Surface Tension:  31.7 dyne/cm 
ensity:  0.976 g/cm3 
Flash Point:  113.7 °C 
Enthalpy of Vaporization:  50.07 kJ/mol 
Boiling Point:  262.9 °C at 760 mmHg 
Vapour Pressure:  0.0106 mmHg at 25°C 

Diethyl dipropylmalonate Uses

  Propanedioic acid,2,2-dipropyl-, 1,3-diethyl ester (CAS NO.6065-63-0) is used as a raw material for medicine and pesticide intermediates.

Diethyl dipropylmalonate Safety Profile

Safety Statements of Propanedioic acid,2,2-dipropyl-, 1,3-diethyl ester (CAS NO.6065-63-0): 24/25
S24/25: Avoid contact with skin and eyes.

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