Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Dihydroterpineol

Related Products

Hot Products

Name

Dihydroterpineol

EINECS 207-871-8
CAS No. 498-81-7 Density 0.9 g/cm3
PSA 20.23000 LogP 2.58360
Solubility N/A Melting Point N/A
Formula C10H20O Boiling Point 212.223 °C at 760 mmHg
Molecular Weight 156.268 Flash Point 89.708 °C
Transport Information N/A Appearance Clear liquid
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 498-81-7 (Dihydroterpineol) Hazard Symbols N/A
Synonyms

p-Menthan-8-ol(6CI,7CI,8CI);8-p-Menthanol;Dihydro-a-terpineol;Cyclohexanemethanol, a,a,4-trimethyl-;2-(4-Methylcyclohexyl)-2-propanol;alpha,alpha,4-Trimethylcyclohexanemethanol;p-Menthan-8-ol;

Article Data 29

Dihydroterpineol Synthetic route

5718-78-5

p-4(8)-Menthene oxide

A

498-81-7

p-menthan-8-ol

B

470-65-5

p-menthane-4-ol

Conditions
ConditionsYield
With lithium In ethylenediamine for 0.5h;A 95%
B 5%
With lithium aluminium tetrahydride; aluminium trichloride In diethyl ether for 8h; Ambient temperature;A 23%
B 70%
98-55-5

terpineol

498-81-7

p-menthan-8-ol

Conditions
ConditionsYield
With palladium on activated charcoal; hydrogen In methanol for 8h;93.5%
With 5%-palladium/activated carbon; hydrogen In methanol for 12h;93.5%
With hydrogen; nickel Hydrogenation;

A

498-81-7

p-menthan-8-ol

B

3901-93-7, 3901-95-9, 21129-27-1

1-methyl-4-(1-methylethyl)cyclohexanol

C

470-65-5

p-menthane-4-ol

Conditions
ConditionsYield
With deuterioporphyrin dimethyl ester ferric chloride In dichloromethane at 130℃; for 18h; Catalytic behavior; Reagent/catalyst; Temperature;A 34.44%
B 5.71%
C 49.16%
With C32H32CoN4O4 at 130℃; under 760.051 Torr; for 17h; Reagent/catalyst; Overall yield = 10.2 %; chemoselective reaction;
917-64-6

methyl magnesium iodide

1879-06-7

4-acetyl-1-methylcyclohexane

498-81-7

p-menthan-8-ol

917-64-6

methyl magnesium iodide

41692-50-6

trans-4-methyl-1-(ethoxycarbonyl)cyclohexane

498-81-7

p-menthan-8-ol

89-78-1

menthol

98-55-5

terpineol

498-81-7

p-menthan-8-ol

Conditions
ConditionsYield
With copper substances of uncertain configuration;
With nickel substances of uncertain configuration;
98-55-5

terpineol

A

1197-01-9

p-cymene-8-ol

B

498-81-7

p-menthan-8-ol

Conditions
ConditionsYield
With palladium-catalysts at 100℃; substances of uncertain configuration;
106-22-9

Citronellol

498-81-7

p-menthan-8-ol

Conditions
ConditionsYield
With benzoic acid In water at 100℃; Product distribution; sealed tube;37 % Chromat.
7133-31-5

4-methylcyclohexanecarboxylic acid ethyl ester

74-88-4

methyl iodide

498-81-7

p-menthan-8-ol

Conditions
ConditionsYield
With magnesium 1.)Et2O; Yield given. Multistep reaction;
4-nitro-benzoyl derivative of (+)-α-terpineol

4-nitro-benzoyl derivative of (+)-α-terpineol

498-81-7

p-menthan-8-ol

Conditions
ConditionsYield
With hydrogenchloride; ethanol; platinum Hydrogenation.Behandlung des Reaktionsprodukts mit aethanol. Alkalilauge; substances of uncertain configuration;

Dihydroterpineol Consensus Reports

Reported in EPA TSCA Inventory.

Dihydroterpineol Specification

The Dihydroterpineol, with the CAS registry number 498-81-7, is also known as alpha,alpha,4-Trimethylcyclohexanemethanol. It belongs to the product category of Pharmaceutical Intermediates. Its EINECS number is 207-871-8. This chemical's molecular formula is C10H20O and molecular weight is 156.27. What's more, its systematic name is 2-(4-Methylcyclohexyl)-2-propanol. Its classification code is Skin / Eye Irritant. 

Physical properties of Dihydroterpineol are: (1)ACD/LogP: 3.092; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 3.09; (4)ACD/LogD (pH 7.4): 3.09; (5)ACD/BCF (pH 5.5): 131.76; (6)ACD/BCF (pH 7.4): 131.76; (7)ACD/KOC (pH 5.5): 1145.38; (8)ACD/KOC (pH 7.4): 1145.38; (9)#H bond acceptors: 1; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 20.23 Å2; (13)Index of Refraction: 1.459; (14)Molar Refractivity: 47.476 cm3; (15)Molar Volume: 173.691 cm3; (16)Polarizability: 18.821×10-24cm3; (17)Surface Tension: 31.10 dyne/cm; (18)Density: 0.9 g/cm3; (19)Flash Point: 89.708 °C; (20)Enthalpy of Vaporization: 52.168 kJ/mol; (21)Boiling Point: 212.223 °C at 760 mmHg; (22)Vapour Pressure: 0.039 mmHg at 25°C.

Preparation: this chemical can be prepared by p-4(8)-Menthene oxide at the ambient temperature. This reaction will need reagents LiAlH4, AlCl3 and solvent diethyl ether with the reaction time of 8 hours. The yield is about 70%.

Dihydroterpineol can be prepared by p-4(8)-Menthene oxide at the ambient temperature

Uses of Dihydroterpineol: it can be used to produce N-p-menth-8-ylacetamide at the temperature of 20 °C. It will need reagent H2SO4 with the reaction time of 2 days. The yield is about 95%.

Dihydroterpineol can be used to produce N-p-menth-8-ylacetamide at the temperature of 20 °C

You can still convert the following datas into molecular structure:
(1)SMILES: OC(C)(C)C1CCC(C)CC1
(2)Std. InChI: InChI=1S/C10H20O/c1-8-4-6-9(7-5-8)10(2,3)11/h8-9,11H,4-7H2,1-3H3
(3)Std. InChIKey: UODXCYZDMHPIJE-UHFFFAOYSA-N

The toxicity data is as follows:  

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rabbit LD50 skin > 5gm/kg (5000mg/kg)   Food and Cosmetics Toxicology. Vol. 12, Pg. 529, 1974.
rat LD50 oral > 5gm/kg (5000mg/kg)   Food and Cosmetics Toxicology. Vol. 12, Pg. 529, 1974.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 498-81-7