Domino reaction of α-acetyl-α-carbamoyl ketene dithioacetals with vilsmeier reagents: A novel and efficient synthesis of 4-halogenated 2(1H)-pyridinones

DOI: 10.1021/jo701742q

Source and publish data:

Journal of Organic Chemistry p. 9259 - 9263 (2007)

Update date:2022-09-26

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Authors:

Chen, Li

Zhao, Yu-Long

Liu, Qun

Cheng, Chao

Piao, Cheng-Ri

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Article abstract of DOI:10.1021/jo701742q

(Chemical Equation Presented) A novel and efficient route to 4-halogenated N-substituted 2(1H)-pyridinones has been developed via a one-pot domino process of readily available α-acetyl-α-carbamoyl ketene dithioacetals with Vilsmeier reagents. These 4-halo

Full text of DOI:10.1021/jo701742q

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