Identification of 4H,6H-[2]benzoxepino[4,5-c][1,2]oxazoles as novel squalene synthase inhibitors

DOI: 10.1016/j.bmcl.2011.04.092

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 3648 - 3653 (2011)

Update date:2022-07-30

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Authors:

Griebenow, Nils

Buchmueller, Anja

Kolkhof, Peter

Schamberger, Jens

Bischoff, Hilmar

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Article abstract of DOI:10.1016/j.bmcl.2011.04.092

Novel squalene synthase inhibitors are disclosed. The design, synthesis, SAR and pharmacological profile of the compounds are discussed.

Full text of DOI:10.1016/j.bmcl.2011.04.092

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