
Journal of Organic Chemistry p. 635 - 648 (1986)
Update date:2022-09-26
Topics:
Ireland, Robert E.
Varney, Michael D.
An approach to the total synthesis of the macrolide antibiotic aglycone chlorothricolide (1b) is presented.Herein is described the synthesis of the advanced intermediate (+/-)-19,20-dihydro-24-O-methylchlorothricolide, methyl ester, ethyl carbonate (34) f
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