New muramyl dipeptide (MDP) mimics without the carbohydrate moiety as potential adjuvant candidates for a therapeutic hepatitis B vaccine (HBV)

DOI: 10.1016/j.bmcl.2011.05.056

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 4292 - 4295 (2011)

Update date:2022-08-03

Topics:

Authors:

Zhao, Nan

Ma, Yao Ma, Yao

Zhang, Shengmei

Fang, Xin

Liang, Zhenglun

Liu, Gang

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Article abstract of DOI:10.1016/j.bmcl.2011.05.056

A series of new muramyl dipeptide (MDP) mimics were designed and synthesized via a solid-phase synthetic route. Their adjuvant activities were evaluated ex vivo for investigation of the synergism of the S_28-39 peptide, which is an MHC class I b

Full text of DOI:10.1016/j.bmcl.2011.05.056

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