Journal of Chemical and Engineering Data p. 103 - 104 (1981)
Update date:2022-08-02
Topics:
Varma, Rajendra S.
Bahadur, Surendra
Agnihotri, Anil K.
Some substituted 6-bromo-3-<(arylamino)methyl>-4(3H)-quinazolinones have been synthesized under the conditions of the Mannich reaction.In addition, a few unsubstituted and substituted 2-styryl-4(3H)-quinazolinones, 6-bromo-2-styryl-4(3H)-quinazolinones, and 6-bromo-2-styryl-3-<4'-(carboethoxy)phenyl>-4(3H)-quinazolinones have also been synthesized by condensing the corresponding 2-methyl derivative with an appropriate aromatic aldehyde.Representative compounds have been screened for their central neural system and antiviral activity.
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