ABNORMAL BASE CATALYSED REACTION OF FORMALDEHYDE AND BENZALDEHYDES WITH 1-(2-HYDROXYPHENYL)-3-PHENYL-1,3-PROPANEDIONE

Article abstract of DOI:10.1016/S0040-4039(00)80065-9

1-(2-Hydroxyphenyl)-3-phenyl-1,3-propanedione (1a) reacts with formaldehyde in the presence of different 1-arylpiperazines (2) to form (1:1) inclusion compounds (3) which on column chromatographic separation yield 4,5;11,12-dibenzo-7-hydroxymethyl-1,3-dioxa-6,10-dioxo-7,9 diphenylcyclododecane (4) and the corresponding 2. 1 react with formaldehyde in the presence of triethylamine to form 3-aroyl-3-(2,3-dihydro-4H-1-benzopyran-4-one-3-ylmethyl)-2,3-dihydro-4H-1-benzopyran-4-one (5) along with benzoic acids and with bezaldehydes in the presence of a base to give 2-aryl-2,3-dihydro-4H-1-benzopyran-4-one (6)