Synthesis of 7-substituted derivatives of 5, 8-dimethylisoquinoline

DOI: 10.3987/COM-07-S(U)38

Source and publish data:

Heterocycles p. 593 - 602 (2007)

Update date:2022-07-30

Topics:

Authors:

Nagao, Yukinori

Hirota, Katsuaki

Tokumaru, Mizuho

Kozawa, Kozo

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.3987/COM-07-S(U)38

7-Bromo-5,8-dimethylisoquinoline was selectively synthesized by the bromination of 5,8-dimethylisoquinoline obtained in five steps from p-xylene as a starting material. Further,7-bromo-5,8-dimethylisoquinolinegave 7-amino-5,8-dimethylisoquinoline by the reaction with ammonia and various 7-anilino-5,8-dimethylisoquinolines via a palladium-catalyzed coupling reaction with anilines.

Full text of DOI:10.3987/COM-07-S(U)38

Products guided by the article

Product name:7-(o-methylanilino)-5,8-dimethylisoquinoline

Cas No:1007382-48-0

R&D Labs maybe for 1007382-48-0

Disynthesis Chemical Technology Co. Ltd.

Contact:+86-571-88194596

Address:Dengyun road 380, Gongshu district, Hangzhou city, China
Hangzhou jls Flame Retardants Chemical Co.,Ltd

Contact:+86-571-87250387/87250386

Address:MOGANSHAN RODA 1418# SHANGCHENG INDUSTRIAL PARK
Anhui Redstar Pharmaceutical Corp., Ltd

Contact:+86-563-5120837

Address:Jingxian Industrial Development Zone, Anhui , China
Shanghai PotentPharm Science and Technology Co.,Ltd

Contact:86-021-51969655

Address:Unit B, Building 18, No.300, Chuantu Rd,Pudong District, Shanghai 201202, China
Guangxi Shanyun Biochemical Science and Technology Co., Ltd

Contact:+86-0772--6828887

Address:#2 Industrial Park of Luzhai County, Liuzhou, Guangxi, China

Relevant to this article

Regio- and chemoselective 6′-N-derivatization of aminoglycosides: Bisubstrate inhibitors as probes to study aminoglycoside 6′-N- acetyltransferases

Doi:10.1002/anie.200501399
(2005)
A convenient method for the preparations of carboxamides and peptides by using di(2-pyridyl) carbonate and O,O′-di(2-pyridyl) thiocarbonate as dehydrating reagents

Doi:10.1246/bcsj.73.2811
(2000)
Cobalt-catalyzed synthesis of tertiary azides from α,α- disubstituted olefins under mild conditions using commercially available reagents

Doi:10.1055/s-2007-1000817
(2007)
Efficient enhancement of DNA cleavage activity by introducing guanidinium groups into diiron(III) complex

Doi:10.1016/j.bmcl.2007.11.001
(2008)
Synthesis and study of dynamic ¹H NMR of carbon-carbon double bond rotation energy barrier in stable phenothiazine phosphorus ylides

Doi:10.1080/10426500601047149
(2007)
Synthesis of 3′,5′-cyclic diguanylic acid (cdiGMP) using 1-(4-chlorophenyl)-4-ethoxypiperidin-4-yl as a protecting group for 2′-hydroxy functions of ribonucleosides

Doi:10.1080/15257770601112762
(2007)

Article Doi