Preparation of Vicinal N-Alkylamino Alcohols via Acylation-Rearrangement of Nitrones Followed by Hydride Reduction

DOI: 10.1021/jo00359a002

Source and publish data:

Journal of Organic Chemistry p. 1383 - 1389 (1986)

Update date:2022-08-05

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Authors:

Coates, Robert M.

Cummins, Clark H.

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Article abstract of DOI:10.1021/jo00359a002

Acylation-rearrangement of N-tert-butyl and N-cyclohexyl nitrones of cyclohexanecarboxaldehyde (1), n-butyraldehyde, isobutyraldehyde, 3-cyclohexenecarboxaldehyde, and α-methylpropionaldehyde gave α-pivaloyloxy imines, which underwent reduction with lithi

Full text of DOI:10.1021/jo00359a002

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