A New Synthetic Entry to Pentacyclic Strychnos Alkaloids. Total Synthesis of (+/-)-Tubifolidine, (+/-)-Tubifoline, and (+/-)-19,20-Dihydroakuammicine

DOI: 10.1021/jo00313a017

Source and publish data:

Journal of Organic Chemistry p. 6299 - 6312 (1990)

Update date:2022-07-31

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Authors:

Amat, Mercedes

Linares, Ana

Bosch, Joan

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Article abstract of DOI:10.1021/jo00313a017

A new strategy for the synthesis of pentacyclic Strychnos alkaloids has been developed.It consists in the closure of the five-membered E ring by cyclization upon the indole 3-position from a suitably N-substituted tetracyclic system embodying rings ABCD o

Full text of DOI:10.1021/jo00313a017

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