Pentakis(trifluoromethyl)phenyl, a sterically crowded and electron-withdrawing group: Synthesis and acidity of pentakis(trifluoromethyl) benzene, -toluene, -phenol, and -aniline

DOI: 10.1021/jo702513w

Source and publish data:

Journal of Organic Chemistry p. 2607 - 2620 (2008)

Update date:2022-08-05

Topics: Synthesis Toluene Phenol Benzene Aniline Experimental Acidity Sterically crowded

Authors:

Kuett, Agnes

Movchun, Valeria

Rodima, Toomas

Dansauer, Timo

Rusanov, Eduard B.

Leito, Ivo

Kaljurand, Ivari

Koppel, Juta

Pihl, Viljar

Koppel, Ivar

Ovsjannikov, Gea

Toom, Lauri

Mishima, Masaaki

Medebielle, Maurice

Lork, Enno

Roeschenthaler, Gerd-Volker

Koppel, Ilmar A.

Kolomeitsev, Alexander A.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo702513w

(Figure Presented) A general route to functionalized pentakis(trifluoromethyl)phenyl (C₆(CF₃)₅) derivatives, promising building blocks for designing novel stable carbenes, radical species, superacids, weakly coordinating a

Full text of DOI:10.1021/jo702513w

Products guided by the article

Product name:tetraethylammonium dicyano[2,3,4,6-tetrakis(trifluoromethyl)phenyl]methanide

Cas No:1018330-48-7

R&D Labs maybe for 1018330-48-7

Xi'an Unique Electronic and Chemical Co., Ltd.

Contact:+86-029-88238008

Address:1703# B BUILDING WEST ELECTRONIC ZONE, XI'AN, CHINA
Linyi Shengxin Pharmaceutical R&D Co., Ltd

Contact:+86-18653953873

Address:West First of Yufeng Road, Yishui County
ShenZhen InnoSyn Biotech Co.,Ltd

website:http://www.innosyns.com

Contact:+86-755-28351685

Address:Floor 5 & 6, Building A1, HAIKEXING Strategic Innovative Industrial Park, 16 BaoShan Road, PingShan District
SuZhou LaiTeou

Contact:+86-0512-88957371

Address:shanghai
Wuhan Better Organic Technology Inc.

Contact:13307163183

Address:Wuhan Economic&Technology Development Zone, Hubei

Relevant to this article

Total Synthesis of (+)-MPC1001B

Doi:10.1002/anie.201507830
(2016)
Hydrogen bonding vs steric gearing in a hexasubstituted benzene

Doi:10.1021/jo800226s
(2008)
Fragment-based lead generation of 5-phenyl-1H-pyrazole-3-carboxamide derivatives as leads for potent factor xia inhibitors

Doi:10.3390/molecules23082002
(2018)
Antitrypanosomal, antileishmanial, and antimalarial activities of quaternary arylalkylammonium 2-amino-4-chlorophenyl phenyl sulfides, a new class of trypanothione reductase inhibitor, and of N-acyl derivatives of 2-amino-4-chlorophenyl phenyl sulfide

Doi:10.1021/jm050819t
(2005)
An improved preparation of 3,4-O-isopropylidene derivatives of α- and β-D-galactopyranosides

Doi:10.1016/0008-6215(88)84011-4
(1988)
4-((R)-2-{[6-((S)-3-Methoxypyrrolidin-1-yl)-2-phenylpyrimidine-4-carbonyl]amino}-3-phosphonopropionyl)piperazine-1-carboxylic Acid Butyl Ester (ACT-246475) and Its Prodrug (ACT-281959), a Novel P2Y₁₂ Receptor Antagonist with a Wider Therapeutic Window in the Rat Than Clopidogrel

Doi:10.1021/acs.jmedchem.5b00933
(2015)

Article Doi