aSYMMETRIC SYNTHESIS IV1. PRAPARATION OF CHIRAL α-AMINONITRILES FROM A NEW N-CYANOMETHYL-1,3-OXAZOLIDINE SYNTHON

DOI: 10.1016/S0040-4039(00)89192-3

Source and publish data:

Tetrahedron Letters p. 3567 - 3570 (1985)

Update date:2022-08-04

Topics:

Authors:

Marco, Jose L.

Royer, Jagues

Husson, Henri-Philippe

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Article abstract of DOI:10.1016/S0040-4039(00)89192-3

The synthesis of (-)-N-cyanomethyl-4-phenyl-1,3-oxazolidine 1 is reported.Good yields and moderate diastereomeric excesses (d.e.s.) of mono- and di-substituted α-aminonitriles were obtained from simple chiral template.

Full text of DOI:10.1016/S0040-4039(00)89192-3

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