ACID CATALYSIS IN ALDOL CONDENSATION OF α-AMINO SILYLKETENE ACETALS. DIASTEREOSELECTIVE SYNTHESIS OF α-AMINO-β-HYDROXYACIDS.

DOI: 10.1016/S0040-4039(00)98679-9

Source and publish data:

Tetrahedron Letters p. 3517 - 3520 (1985)

Update date:2022-08-03

Topics:

Authors:

Guanti, Giuseppe

Banfi, Luca

Narisano, Enrica

Scolastico, Carlo

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Article abstract of DOI:10.1016/S0040-4039(00)98679-9

The aldol-type condensation between α-dibenzylamino trimethylsilyl ketene acetals and various achiral and chiral aldehydes in the presence of a Lewis acid furnishes α-amino-β-hydroxyacids in moderate yields with preferential C₂-C₃ th

Full text of DOI:10.1016/S0040-4039(00)98679-9

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