Synthesis and antidepressant activity of 5-(1-aryl-4-piperazino)methyl-2-amino-2-oxazolines

DOI: 10.1016/0223-5234(92)90177-3

Source and publish data:

European Journal of Medicinal Chemistry p. 437 - 442 (1992)

Update date:2022-08-04

Topics:

Authors:

Bosc Bosc

Jarry Jarry

Carpy Carpy

Panconi Panconi

Descas Descas

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0223-5234(92)90177-3

The synthesis of 20 5-(1-aryl-4-piperazino)methyl-2-amino-2-oxazolines is described. Antidepressant activity was observed in mice using classical screening tests. Structure-activity relationships were studied and correlated with the nature of the aromatic

Full text of DOI:10.1016/0223-5234(92)90177-3

Products guided by the article

Product name:1-Chloro-3-(4-p-tolyl-piperazin-1-yl)-propan-2-ol

Cas No:1026372-84-8

R&D Labs maybe for 1026372-84-8

Second Pharma Co., Ltd

Contact:+86-575-82733999 0575-82732999

Address:hangzhou gulf fine chemical zone,shangyu city,zhejiang province
HangZhou HuaYe Chemical Technology Co.,Ltd

Contact:+86-13505815007

Address:hangzhou
ChengduChroma-BiotechCo.,Ltd.

Contact:86-28-61993785

Address:No.70-13-21, North Section, Erhuan
Jiangxi Runhao Pharmaceutical Stock Co.,ltd.

Contact:86-791-8861 9931

Address:Industrial Area of Shuibian town,Xiajiang county,Ji'an city,Jiangxi Province.
QINGDAO TAOSIGN INTERNATIONAL TRADE CO.,LIMITED

Contact:+86-0532-82683616

Address:RM1402, Doublestar Seacoase 7#, No. 5 Guizhou Road, Qingdao, Shandong, China

Relevant to this article

Doi:10.1016/S0040-4020(01)99418-9
(1966)
Concise, stereoselective route to the four diastereoisomers of 4-methylproline

Doi:10.1021/np070673w
(2008)
Ac-<3- and 4-Alkylthioproline³¹>-CCK₄ Analogs: Synthesis and Implications for the CCK-B Receptor-Bound Conformation

Doi:10.1021/jm00001a019
(1995)
1,2,4-Triazolo[1,2-a]benzotriazoles: First examples of a novel ring system

Doi:10.1016/S0040-4039(01)02023-8
(2001)
Highly effective and enantioselective α-amination of aldehydes promoted by chiral proline amide-thiourea bifunctional catalysts

Doi:10.1016/j.tetlet.2010.07.042
(2010)
Central cholinergic agents. IV. Synthesis and acetylcholinesterase inhibitory activities of ω-[N-ethyl-N-(phenylmethyl)amino]-1-phenyl-1-alkanones and their analogues with partial conformational restriction

Doi:10.1248/cpb.41.529
(1993)

Article Doi