Synthesis and antidepressant activity of 5-(1-aryl-4-piperazino)methyl-2-amino-2-oxazolines

DOI: 10.1016/0223-5234(92)90177-3

Source and publish data:

European Journal of Medicinal Chemistry p. 437 - 442 (1992)

Update date:2022-08-04

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Authors:

Bosc Bosc

Jarry Jarry

Carpy Carpy

Panconi Panconi

Descas Descas

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Article abstract of DOI:10.1016/0223-5234(92)90177-3

The synthesis of 20 5-(1-aryl-4-piperazino)methyl-2-amino-2-oxazolines is described. Antidepressant activity was observed in mice using classical screening tests. Structure-activity relationships were studied and correlated with the nature of the aromatic

Full text of DOI:10.1016/0223-5234(92)90177-3

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