Journal of the American Chemical Society p. 7921 - 7925 (1989)
Update date:2022-09-26
Topics:
Fuji, Kaoru
Node, Manabu
Nagasawa, Hideko
Naniwa, Yoshimitsu
Taga, Tooru
et al.
The reactions of chiral nitro enamines 2a-c with zinc enolates 4-6 of α-substituted δ-lactones afforded α,α-disubstituted δ-lactones with a high ee through an addition-elimination process.The best results were obtained with the reaction of 2c with 5.Michael-type addition of the enolate onto the nitro enamine is kinetically controlled and decides the absolute stereochemistry of the product.A cyclic transition model is proposed to rationalize the S-selectivity.
View MoreContact:0792-8228321
Address:10TH Floor No.121 binjiang Road Xunyang District
Zhejiang Sucon Silicone Co.,Ltd
Contact:+86-575-88046692
Address:Qisheng Rd., Paojiang Industrial Zone, Shaoxing, Zhejiang, China.
website:http://www.enbridgepharm.com
Contact:+86-510-83591909
Address:Huishan Zone, Wuxi City, Jiangsu Province, P.R.China
Qingdao S. H. Huanyu Imp. & Exp. Co., Ltd.
Contact:86-532-88250866
Address:Room 615, World Trade Centre Building B, Hongkong Middle Roda 6#, Qingdao, Shandong, China
Nanjing Chemlin Chemical Co., Ltd.
website:http://www.echemlin.cn
Contact:+86-25-83697070
Address:Rm.902 Longyin Plaza, No. 217 Zhongshan Rd.(N) Nanjing 210009,China
Doi:10.1039/c0ob01268h
(2011)Doi:10.1134/S0023158410040105
(2010)Doi:10.1039/b719776d
(2008)Doi:10.1016/j.ejmech.2011.01.035
(2011)Doi:10.1021/jo982015+
(1999)Doi:10.1080/00397910008087030
(2000)
